Human Anti-ERBB2 Rcombinant Antibody (TP-083CL) (CAT#: TP-083CL)
A recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein. Produced in CHO cell culture.
Specific Inquiry
SPR
Figure 1 Trastuzumab (TP-083CL) in SPR
SPR assays of TP-083CL.
The affinity of Trastuzumab (TP-083CL) was determined by SPR.
Captured TP-083CL on CM5 Chip via Anti-Human IgG (Fc) can bind Human ERBB2 protein with an affinity constant of 1.45 nM as determined in a SPR assay (Biacore 8K).
Specifications
- Type
- Biotech
Target
- Function
- Humanized mAb that binds Her2/Neu cell surface receptor and controls cancer cell growth
Related Resources
Please refer to Trastuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Trastuzumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Customer Reviews and Q&As
Customer Review
Q&As
Laura Brown
Ideal for HER2 Research
Ideal for HER2 Research
The Trastuzumab has been excellent for our HER2 research. Its specificity and sensitivity are top-notch, providing clear and reliable results. This antibody has significantly improved the accuracy of our experiments and saved us a lot of troubleshooting time.
03-Dec-23
Emily Lewis
Reliable in Immunoassays
Reliable in Immunoassays
We incorporated this antibody into our immunoassays, and it has been a great asset. The specificity for HER2 is precise, allowing for accurate detection and analysis. The reliable performance has made it an invaluable tool in our lab.
09-Aug-22
John Carter
Consistent and Effective
Consistent and Effective
This antibody has proven to be consistent and effective in our various assays. The high-quality, reproducible results have significantly improved our experiments, making it a crucial part of our research toolkit. The strong affinity and specificity for HER2 have been particularly beneficial.
26-Sep-21
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TP-083CL, RRID: AB_3112050)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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