Z-domain of protein A scaffold protein anti-Human apolipoprotein A-1 variant
CAT#: SZA-L228
This human apolipoprotein A-1 variant specific binding protein (Z-domain of protein A) was investigated by an α-helix shuffling strategy. The primary scaffold protein was from a naive combinatorial library of the three-helix bundle Z domain derived from staphylococcal protein A. A hierarchical library was constructed through selective re-randomization of six amino acid positions in one of the two α-helices of the domain, making up the Taq DNA polymerase binding surface. After selections using monovalent phage display technology, second generation variants were identified having affinities for human apolipoprotein A-1 variant as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line Hep G2
Immunofluorescent staining of human cell line Hep G2 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46715/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human endometrium
Immunohistochemical staining of human endometrium shows distinct positivity in plasma.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46715/126376_B_5_3_selected.jpg
Normal Tissue
Figure 3 IHC staining of human gallbladder
Immunohistochemical staining of human gallbladder shows distinct positivity in plasma.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16778/39553_A_6_4_selected.jpg
Subcellular Location
Figure 4 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46715/807_G3_2_blue_red_green.jpg
Subcellular Location
Figure 5 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46715/846_G3_4_blue_red_green.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enriched (Hep G2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118137-APOA1
❮
❯
Specifications
- Scaffold Name
- Z-domain of protein A
- Origin
- Staphylococcal protein A
- Core Structure
- 3-α helixes
- Variable Regions
- 13 Residues on first and second helix surface
- Target
- Human apolipoprotein A-1 variant
- Species Reactivity
- Human
- Expression Host
- E. coli
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
- Alternative Names
- Staphylococcal protein A; Z-domain of protein A; apo(a)
- Gene ID
- 335
- UniProt ID
- A0A024R3E3
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for SZA-L228. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "APOA1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-73-F(E) | Recombinant Anti-human APOA1 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| MHH-73-F(E) | Recombinant Human Anti-human APOA1 Antibody Fab Fragment | ELISA, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-73-S(P) | Recombinant Anti-human APOA1 Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| MHH-73-S(P) | Recombinant Human Anti-human APOA1 Antibody scFv Fragment | FC, RIA, Biosensors, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-071 | Recombinant Anti-human APOA1 VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-73 | Recombinant Human Anti-human APOA1 Antibody | IP, IF, Biosensors, FuncS | IgG |
| MRO-0111-CN | Mouse Anti-APOA1 Recombinant Antibody (clone B5-F11) | WB, IF, IHC | Mouse IgG1 |
| MRO-0112-CN | Rabbit Anti-APOA1 Recombinant Antibody (clone JF0548) | WB, IF, IHC, IP | Rabbit IgG |
| ZG-0296F | Mouse Anti-ApoA1 Recombinant Antibody (ZG-0296F) | WB, ELISA | Mouse IgG |
| VS3-WK1543 | Mouse Anti-APOA1 Recombinant Antibody (clone No:8-F0) | WB | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0048MZ | Chicken Anti-APOA1 Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
| BRD-0784MZ | Chicken Anti-Apolipoprotein A1 Polyclonal IgY | ICC, IF, IHC, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0204 | Hi-Affi™ Rabbit Anti-APOA1 Recombinant Antibody (clone DS204AB) | IF, IHC-P, IP, WB, sELISA | Rabbit IgG |
| MOR-4531 | Hi-Affi™ Rabbit Anti-APOA1 Recombinant Antibody (clone TH39DS) | WB, IF, ICC, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-006CN | Mouse Anti-APOA1 Recombinant Antibody (clone AI-11) | WB, ELISA, IHC | Mouse IgG |
| NS-006CN-F(E) | Mouse Anti-APOA1 Recombinant Antibody (clone AI-11); Fab Fragment | WB, ELISA, IHC | Mouse Fab |
| NS-006CN-S(P) | Mouse Anti-APOA1 Recombinant Antibody (clone AI-11); scFv Fragment | WB, ELISA, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1504 | AbPlus™ Anti-APOA1 Magnetic Beads (VS-0724-YC1504) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY131 | Anti-APOA1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY449 | Anti-Mouse APOA1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY448 | Anti-Human APOA1 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Application: FuncS, IF, Neut, ELISA, FC, IP, WB
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: ELISA, SPR, Inhib, FuncS
Application: Neut, Inhib, FC, ELISA
Application: WB, ELISA, IF
Application: ELISA, IHC, FC, IP, IF, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
