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APOA1

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This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]

Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
ELISA, WB, Dot, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
ELISA, IP, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
ELISA, WB, FuncS
Derivation:
Human
Species Reactivity:
Human
Type:
IgG
Application:
IP, IF, Biosensors, FuncS
Derivation:
Human
Species Reactivity:
Human
Type:
scFv
Application:
FC, RIA, Biosensors, FuncS
Species Reactivity:
Human
Type:
IgG
Application:
WB, ELISA, IHC
Species Reactivity:
Human
Type:
Fab
Application:
WB, ELISA, IHC
Species Reactivity:
Human
Type:
scFv
Application:
WB, ELISA, IHC
Species Reactivity:
Human
Type:
Mouse IgG1
Application:
WB, IF, IHC
Species Reactivity:
Human, Mouse
Type:
Rabbit IgG
Application:
WB, IF, IHC, IP
Species Reactivity:
Human
Type:
Mouse antibody
Application:
FC
Species Reactivity:
Human
Type:
Chicken antibody
Application:
Indirect ELISA, WB
Derivation:
Phage display library screening
Species Reactivity:
Human
Type:
IgG
Application:
ICC/IF, IHC-P, IP, WB, sELISA
Species Reactivity:
Human
Type:
Mouse IgG1, κ
Application:
ELISA
Derivation:
Human
Species Reactivity:
Human
Type:
Fab
Application:
ELISA, IF, FuncS
Species Reactivity:
Human
Type:
Mouse Fab
Application:
ELISA
Species Reactivity:
Human
Type:
Mouse scFv
Application:
ELISA
Species Reactivity:
Human
Type:
Llama VHH
Application:
WB, ELISA, IP, FuncS
Scaffold Name:
Z-domain of protein A
Target:
Human apolipoprotein A-1 variant
Species Reactivity:
Human
Derivation:
Phage display
Species Reactivity:
Human, Mouse, Rat
Type:
Chicken antibody
Application:
ICC, IF, IHC, WB
Species Reactivity:
Human, Rat
Type:
IgG
Application:
WB, IF, ICC, ELISA
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