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APOA1
Loading...Anti-APOA1 Products
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: IP, IF, Biosensors, FuncS
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- Recombinant Mouse Anti-APOA1 Antibody (VS-0923-FY20) (VS-0923-FY20)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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- Rabbit Anti-APOA1 Polyclonal Antibody (MRO-1658-CN) (MRO-1658-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Rabbit Anti-APOA1 Recombinant Antibody (clone JF0548) (MRO-0112-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
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- Mouse Anti-APOA1 Recombinant Antibody (clone B5-F11) (MRO-0111-CN)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IF, IHC
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- Mouse Anti-APOA1 Recombinant Antibody (clone MabA34) (FAMAB-0012CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA
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- Mouse Anti-APOA1 Recombinant Antibody (clone 20I20) (MOB-0663MZ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
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- AbPlus™ Anti-APOA1 Magnetic Beads (VS-0724-YC1504) (VS-0724-YC1504)
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- Target: APOA1
- Target Species: Human
- Application: IP, Protein Purification
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- Recombinant Anti-human APOA1 Antibody scFv Fragment (MOB-73-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: FC, RIA, Biosensors, FuncS
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- Recombinant Human Anti-human APOA1 Antibody Fab Fragment (MHH-73-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, IF, FuncS
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- Recombinant Anti-human APOA1 Antibody Fab Fragment (MOB-73-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, IP, FuncS
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- Scaffold Name: Z-domain of protein A
- Target: Human apolipoprotein A-1 variant
- Species Reactivity: Human
- Derivation: Phage display
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- Anti-Human APOA1 Immunohistochemistry Kit (VS-0525-XY448)
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- Species Reactivity: Human
- Target: APOA1
- Application: IHC
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- Anti-Mouse APOA1 Immunohistochemistry Kit (VS-0525-XY449)
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- Species Reactivity: Human, Mouse
- Target: APOA1
- Application: IHC
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- Anti-APOA1 Immunohistochemistry Kit (VS-0325-XY131)
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- Species Reactivity: Human
- Target: APOA1
- Application: IHC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IF, IHC-P, IP, WB, sELISA
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- Chicken Anti-Apolipoprotein A1 Polyclonal IgY (BRD-0784MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: ICC, IF, IHC, WB
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- Chicken Anti-APOA1 Polyclonal IgY (BRD-0048MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: Indirect ELISA, WB
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.
Protein class
Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Group enriched (Hepatocytes, Proximal enterocytes)
Immune cell specificity
Immune cell enhanced (plasmacytoid DC)
Cell line specificity
Cell line enriched (Hep G2)
Interaction
Homodimer (By similarity). Interacts with NAXE and CLU (PubMed:1742316, 11991719). Component of a sperm activating protein complex (SPAP), consisting of APOA1, an immunoglobulin heavy chain, an immunoglobulin light chain and albumin (PubMed:1909888). Interacts with NDRG1 (PubMed:15922294). Interacts with SCGB3A2 (PubMed:12847263). Interacts with NAXE and YJEFN3 (PubMed:23719382).
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