This insulin specific binding protein (Z-domain of protein A) was investigated by an α-helix shuffling strategy. The primary scaffold protein was from a naive combinatorial library of the three-helix bundle Z domain derived from staphylococcal protein A. A hierarchical library was constructed through selective re-randomization of six amino acid positions in one of the two α-helices of the domain, making up the Taq DNA polymerase binding surface. After selections using monovalent phage display technology, second generation variants were identified having affinities for insulin as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-385CL | Anti-Human IGF1 Recombinant Antibody (BI 836845) | WB, FuncS | Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1072CQ | Mouse Anti-IGF1 Recombinant Antibody (clone M23) | Neut, FC, ICC, IF | Mouse IgG1, κ |
NEUT-1073CQ | Mouse Anti-IGF1 Recombinant Antibody (clone SPM406) | WB, Neut, FC, ICC, IF, IHC-P, IP | Mouse IgG1, κ |
NEUT-1074CQ | Hamster Anti-Igf1 Recombinant Antibody (clone CBL534) | WB, ELISA, Neut | Hamster IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1754 | Rabbit Anti-IGF1 Recombinant Antibody (clone DS1754AB) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0770-CN-S(P) | Human Anti-IGF1 Recombinant Antibody; scFv Fragment (HPAB-0770-CN-S(P)) | WB, FC | Human scFv |
HPAB-0771-CN-S(P) | Human Anti-IGF1 Recombinant Antibody; scFv Fragment (HPAB-0771-CN-S(P)) | WB, FC | Human scFv |
HPAB-0038LY-S(P) | Human Anti-IGF1 Recombinant Antibody; scFv Fragment (HPAB-0038LY-S(P)) | WB | Human scfv |
HPAB-646-FY-S(P) | Mouse Anti-IGF1 Recombinant Antibody (clone MuEM164); scFv Fragment | Inhib, FC | Mouse scFv |
HPAB-647-FY-S(P) | Human Anti-IGF1 Recombinant Antibody (clone huEM164 V1.0); scFv Fragment | Inhib, FC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0770-CN-F(E) | Human Anti-IGF1 Recombinant Antibody; Fab Fragment (HPAB-0770-CN-F(E)) | WB, FC | Human Fab |
HPAB-0771-CN-F(E) | Human Anti-IGF1 Recombinant Antibody; Fab Fragment (HPAB-0771-CN-F(E)) | WB, FC | Human Fab |
HPAB-0160-YJ-F(E) | Human Anti-IGF1 Recombinant Antibody; Fab Fragment (HPAB-0160-YJ-F(E)) | ELISA, Neut, FuncS | Human Fab |
HPAB-0161-YJ-F(E) | Human Anti-IGF1 Recombinant Antibody; Fab Fragment (HPAB-0161-YJ-F(E)) | ELISA, Neut, FuncS | Human Fab |
HPAB-0711-FY-S(P) | Mouse Anti-IGF1 Recombinant Antibody (clone AB010); Fab Fragment | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0160-YJ | Human Anti-IGF1 Recombinant Antibody (HPAB-0160-YJ) | ELISA, Neut, FuncS | Human IgG1 |
VS1-YJ107 | Mouse Anti-IGF1 Recombinant Antibody (clone 7973), HRP | ELISA, IHC-P, IHC-Fr | Mouse IgG1 |
VS1-YJ108 | Mouse Anti-IGF1 Recombinant Antibody (clone 7973) | ELISA, IHC-Fr, IHC-P | Mouse IgG1 |
VS1-YJ109 | Mouse Anti-IGF1 Recombinant Antibody (clone 7973), FITC | ELISA, IHC-P, IHC-Fr | Mouse IgG1 |
VS3-WK1283 | Mouse Anti-IGF1 Recombinant Antibody (VS3-WK1283) | IHC | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0897 | PE-H-2Db/Human IGF1 (SHLVEALYL) MHC Tetramer | FCM, IHC | |
MHC-CN0898 | APC-H-2Db/Human IGF1 (SHLVEALYL) MHC Tetramer | FCM, IHC | |
MHC-CN0899 | FITC-H-2Db/Human IGF1 (SHLVEALYL) MHC Tetramer | FCM, IHC | |
MHC-CN0900 | H-2Db/Human IGF1 (SHLVEALYL) MHC Tetramer | FCM, IHC |
There are currently no Customer reviews or questions for SZA-L233. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.