Human Anti-IGF1 (clone Cixutumumab) scFv-Fc Chimera (CAT#: VS-0325-FY73)
The Anti-IGF1 scFv-Fc Antibody targets the Insulin-like Growth Factor 1 (IGF1), a key regulator of cell growth and differentiation. It offers high specificity and can be used to study the role of IGF1 in various biological processes. This antibody is suitable for use in cell biology and molecular biology research.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human colon
(Immunohistochemical staining of human colon shows plasma positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/ihc_selected.jpg
(Immunohistochemical staining of human colon shows plasma positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/ihc_selected.jpg
Figure 2 Colon
(Endothelial cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_7_3.jpg
(Endothelial cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_7_3.jpg
Figure 3 Rectum
(Glandular cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_4_3.jpg
(Glandular cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_4_3.jpg
Figure 4 Liver
(Hepatocytes Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_9_4.jpg
(Hepatocytes Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_9_4.jpg
Figure 5 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_4_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_4_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, HDLM-2, K-562, Karpas-707, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000017427-IGF1/
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000017427-IGF1/
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human IGF1
- Species Reactivity
- Human
- Clone
- Cixutumumab
- Applications
- ELISA, Flow Cytometry
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Insulin Like Growth Factor 1
- Gene ID
- 3479
- UniProt ID
- P05019
- Long Name
- Insulin Like Growth Factor 1
- Sequence Similarities
- Belongs to the insulin family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Modification sites at PhosphoSitePlus
Modification sites at neXtProt
- Protein Refseq
- XP_016874748.1; XP_016874751.1; XP_016874752.1; XP_054227926.1; XP_054227927.1
- Function
- IGF1 (Insulin-like growth factor 1) is a hormone that plays a crucial role in growth and development. It stimulates cell proliferation and differentiation, and is involved in various physiological processes.
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
Insulin Signaling Pathway
Endocrine Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1353z | Mouse Anti-IGF1 Recombinant Antibody (clone 23C1) | FC, IF, Neut | Mouse IgG1, κ |
| HPAB-646-FY | Mouse Anti-IGF1 Recombinant Antibody (clone MuEM164) | FC, ELISA, Inhib, Cyt | Mouse IgG |
| HPAB-647-FY | Human Anti-IGF1 Recombinant Antibody (clone huEM164 V1.0) | Inhib | Human IgG |
| HPAB-0160-YJ | Human Anti-IGF1 Recombinant Antibody (HPAB-0160-YJ) | ELISA, Neut, FuncS | Human IgG1 |
| HPAB-0161-YJ | Human Anti-IGF1 Recombinant Antibody (HPAB-0161-YJ) | ELISA, Neut, FuncS | Human IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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