Human Anti-IGF1 (clone Cixutumumab) scFv-Fc Chimera
CAT#: VS-0325-FY73
The Anti-IGF1 scFv-Fc Antibody targets the Insulin-like Growth Factor 1 (IGF1), a key regulator of cell growth and differentiation. It offers high specificity and can be used to study the role of IGF1 in various biological processes. This antibody is suitable for use in cell biology and molecular biology research.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human colon
Immunohistochemical staining of human colon shows plasma positivity.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/ihc_selected.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_7_3.jpg
Normal Tissue
Figure 3 Rectum
Glandular cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_4_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_9_4.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48946/110992_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, HDLM-2, K-562, Karpas-707, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000017427-IGF1/
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Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human IGF1
- Species Reactivity
- Human
- Clone
- Cixutumumab
- Applications
- ELISA, Flow Cytometry
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Insulin Like Growth Factor 1
- Gene ID
- 3479
- UniProt ID
- P05019
- Long Name
- Insulin Like Growth Factor 1
- Sequence Similarities
- Belongs to the insulin family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Modification sites at PhosphoSitePlus
Modification sites at neXtProt
- Protein Refseq
- XP_016874748.1; XP_016874751.1; XP_016874752.1; XP_054227926.1; XP_054227927.1
- Function
- IGF1 (Insulin-like growth factor 1) is a hormone that plays a crucial role in growth and development. It stimulates cell proliferation and differentiation, and is involved in various physiological processes.
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Related Signaling Pathways
Insulin Signaling Pathway
Related Diseases
Endocrine Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "IGF1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1353z | Mouse Anti-IGF1 Recombinant Antibody (clone 23C1) | FC, IF, Neut | Mouse IgG1, κ |
| HPAB-0038-YC | Mouse Anti-IGF1 Recombinant Antibody (HPAB-0038-YC) | ELISA | Mouse IgG |
| HPAB-0039-YC | Human Anti-IGF1 Recombinant Antibody (HPAB-0039-YC) | ELISA, Stim, Neut | Human IgG1 |
| HPAB-0161-YJ | Human Anti-IGF1 Recombinant Antibody (HPAB-0161-YJ) | ELISA, Neut, FuncS | Human IgG1 |
| VS3-WK1283 | Mouse Anti-IGF1 Recombinant Antibody (VS3-WK1283) | IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-385CL | Anti-Human IGF1 Recombinant Antibody (TAB-385CL) | WB, FuncS | Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1072CQ | Mouse Anti-IGF1 Recombinant Antibody (clone M23) | Neut, FC, ICC, IF | Mouse IgG1, κ |
| NEUT-1073CQ | Mouse Anti-IGF1 Recombinant Antibody (clone SPM406) | WB, Neut, FC, ICC, IF, IHC-P, IP | Mouse IgG1, κ |
| NEUT-1074CQ | Hamster Anti-Igf1 Recombinant Antibody (clone CBL534) | WB, ELISA, Neut | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1754 | Rabbit Anti-IGF1 Recombinant Antibody (clone DS1754AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0038-YC-F(E) | Mouse Anti-IGF1 Recombinant Antibody; Fab Fragment (HPAB-0038-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-0039-YC-F(E) | Human Anti-IGF1 Recombinant Antibody; Fab Fragment (HPAB-0039-YC-F(E)) | ELISA, Stim, Neut | Human Fab |
| HPAB-0770-CN-F(E) | Human Anti-IGF1 Recombinant Antibody; Fab Fragment (HPAB-0770-CN-F(E)) | WB, FC | Human Fab |
| HPAB-0771-CN-F(E) | Human Anti-IGF1 Recombinant Antibody; Fab Fragment (HPAB-0771-CN-F(E)) | WB, FC | Human Fab |
| HPAB-0160-YJ-F(E) | Human Anti-IGF1 Recombinant Antibody; Fab Fragment (HPAB-0160-YJ-F(E)) | ELISA, Neut, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0770-CN-S(P) | Human Anti-IGF1 Recombinant Antibody; scFv Fragment (HPAB-0770-CN-S(P)) | WB, FC | Human scFv |
| HPAB-0771-CN-S(P) | Human Anti-IGF1 Recombinant Antibody; scFv Fragment (HPAB-0771-CN-S(P)) | WB, FC | Human scFv |
| HPAB-0038LY-S(P) | Human Anti-IGF1 Recombinant Antibody; scFv Fragment (HPAB-0038LY-S(P)) | WB | Human scfv |
| HPAB-0160-YJ-S(P) | Human Anti-IGF1 Recombinant Antibody; scFv Fragment (HPAB-0160-YJ-S(P)) | ELISA, Neut, FuncS | Human scFv |
| HPAB-0161-YJ-S(P) | Human Anti-IGF1 Recombinant Antibody; scFv Fragment (HPAB-0161-YJ-S(P)) | ELISA, Neut, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0897 | PE-H-2Db/Human IGF1 (SHLVEALYL) MHC Tetramer | FCM, IHC | |
| MHC-CN0898 | APC-H-2Db/Human IGF1 (SHLVEALYL) MHC Tetramer | FCM, IHC | |
| MHC-CN0899 | FITC-H-2Db/Human IGF1 (SHLVEALYL) MHC Tetramer | FCM, IHC | |
| MHC-CN0900 | H-2Db/Human IGF1 (SHLVEALYL) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3427 | Anti-IGF1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3428 | Anti-Mouse IGF1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3429 | Anti-Rabbit IGF1 Immunohistochemistry Kit | IHC |
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