A*02:01/Human MART-1 (ELAGIGILTV) MHC Monomer
CAT#: MHC-YF001
This product is a MHC monomer of biotinylated peptide/MHC complex composed MART-1-derived peptide of ELAGIGILTV sequence covering 26-35 and A*02:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Gene Expression
Normal Tissue
Figure 1 High expression in skin 1
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_B_8_1_val_selected.jpg
Normal Tissue
Figure 2 Low expression in liver
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_8_4_val_selected.jpg
Normal Tissue
Figure 3 Testis
Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_5_6.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enriched (SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120215-MLANA
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Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- MART-1
- Antigen Species
- Human
- Peptide
- ELAGIGILTV
- Range
- 26-35
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
- Alternative Names
- MART1; MART-1
- Gene ID
- 2315
- UniProt ID
- Q16655
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High-Quality Product
The quality of this MHC Pentamer is evident from the high specificity and low background staining. It's a high-quality reagent for T-cell immunology studies.
Clear and Precise Staining
The staining results were clear and precise, making it easy to distinguish between different T-cell populations in my samples.
Versatile Applications
This product has proven to be versatile for multiple types of assays, from flow cytometry to cytometric bead arrays, delivering consistent performance.
Q&As
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Can I use this product for ELISPOT assays?
A: Although its primary purpose is flow cytometry, it might be modified and used in ELISPOT tests to examine the release of cytokines from certain T-cells.
-
What kind of cells can I use this with?
A: Tumor-infiltrating lymphocytes (TILs), peripheral blood mononuclear cells (PBMCs), and other isolated T-cell populations can all be treated with this MHC Pentamer.
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Does this antibody come with a datasheet that includes experimental protocols?
A: Yes, a thorough datasheet containing precise experimental guidelines and usage instructions is included with the antibody.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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