FITC-A*02:01/Human PTPRN (MVWESGCTV) MHC Tetramer

CAT#: MHC-CN1171

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • PTPRN
  • Antigen Species
  • Human
  • Peptide
  • MVWESGCTV
  • Conjugate
  • FITC
  • Application
  • FCM, IHC

Target

  • Antigen Introduction
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
  • Alternative Names
  • IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP
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Protocol & Troubleshooting

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