A*03:01/Human TERT (SVLNYERARR) MHC Tetramer (CAT#: MHC-CN1260)


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*03:01
  • Class
  • Class I
  • Antigen
  • TERT
  • Antigen Species
  • Human
  • Peptide
  • SVLNYERARR
  • Conjugate
  • Unconjugated
  • Application
  • FCM, IHC

Target

  • Antigen Introduction
  • Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.
  • Alternative Names
  • TP2; TRT; CMM9; EST2; TCS1; hTRT; DKCA2; DKCB4; hEST2; PFBMFT1

Downloads

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See other products for "TERT"

Fab Fragment Antibody

scFv Fragment Antibody

Single-domain Antibody

CAT Product Name Application Type
NABL-050 Recombinant Anti-human TERT VHH Single Domain Antibody WB, ELISA, IP, FuncS Llama VHH

Intrabody

CAT Product Name Application Type
IAB-B046(A) Recombinant Anti-human TERT Intrabody [(D-Arg)9] PCA, Neut, FuncS scFv-(D-Arg)9
IAB-B046(G) Recombinant Anti-human TERT Intrabody [+36 GFP] WB, Neut, FuncS scFv-(+36GFP)
IAB-B046(T) Recombinant Anti-human TERT Intrabody [Tat] WB, ICC, Neut, FuncS scFv-Tat

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0581MZ Chicken Anti-TERT Polyclonal IgY WB Chicken antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3533 Rabbit Anti-TERT Recombinant Antibody (clone DS3533AB) FC, ICC, IF, IHC-Fr, IHC-P, IP, WB Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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