AbPlus™ Anti-ACVRL1 Magnetic Beads (VS-0724-YC1261) (CAT#: VS-0724-YC1261)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-ACVRL1 specific antibody

• Target
• ACVRL1

• Immunogen
• Recombinant human ALK-1/ACVRL1, aa 1-118.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]

• Alternative Names
• Activin A Receptor Like Type 1; TGF-B Superfamily Receptor Type I; Activin A Receptor Type II-Like 1; Activin A Receptor Type IL; EC 2.7.11.30; ACVRLK1; TSR-I; ALK-1; ALK1;

• Gene ID
• 94

• UniProt ID
• P37023

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