AbPlus™ Anti-ACVRL1 Magnetic Beads (VS-0724-YC1261)
CAT#: VS-0724-YC1261
The AbPlus Anti-ACVRL1 Magnetic Beads (VS-0724-YC1261) is an innovative affinity resin which is bound with anti-ACVRL1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of ACVRL1 protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows strong granular cytoplasmic positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_7_3.jpg
Normal Tissue
Figure 4 Gallbladder
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_5_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Leydig cells Staining: Low Intensity: Weak Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, EFO-21, HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000139567-ACVRL1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-ACVRL1 specific antibody
- Target
- ACVRL1
- Immunogen
- Recombinant human ALK-1/ACVRL1, aa 1-118.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]
- Alternative Names
- Activin A Receptor Like Type 1; TGF-B Superfamily Receptor Type I; Activin A Receptor Type II-Like 1; Activin A Receptor Type IL; EC 2.7.11.30; ACVRLK1; TSR-I; ALK-1; ALK1;
- Gene ID
- 94
- UniProt ID
- P37023
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ACVRL1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0065 | Hi-Affi™ Rabbit Anti-ACVRL1 Recombinant Antibody (clone DS65AB) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-003ML | Anti-Human ACVRL1 Recombinant Antibody (TAB-003ML) | ELISA, IHC, FC, IP, IF, Inhib | IgG2, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0136-CN-F(E) | Human Anti-ACVRL1 Recombinant Antibody (clone MOR05444); Fab Fragment | ELISA, IHC | Human Fab |
| HPAB-0137-CN-F(E) | Human Anti-ACVRL1 Recombinant Antibody (clone MOR05377); Fab Fragment | ELISA, IHC | Human Fab |
| HPAB-J0024-YC-F(E) | Human Anti-ACVRL1 Recombinant Antibody; Fab Fragment (HPAB-J0024-YC-F(E)) | ELISA, FC, WB | Human Fab |
| HPAB-J0025-YC-F(E) | Human Anti-ACVRL1 Recombinant Antibody; Fab Fragment (HPAB-J0025-YC-F(E)) | ELISA, FC, WB | Human Fab |
| HPAB-J0026-YC-F(E) | Human Anti-ACVRL1 Recombinant Antibody; Fab Fragment (HPAB-J0026-YC-F(E)) | ELISA, FC, WB, Inhib, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-003ML | Afuco™ Anti-ACVRL1 ADCC Recombinant Antibody, ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0024-YC | Human Anti-ACVRL1 Recombinant Antibody (HPAB-J0024-YC) | ELISA, FC, WB | Human IgG1 |
| HPAB-J0025-YC | Human Anti-ACVRL1 Recombinant Antibody (HPAB-J0025-YC) | ELISA, FC, WB | Human IgG |
| HPAB-J0026-YC | Human Anti-ACVRL1 Recombinant Antibody (HPAB-J0026-YC) | ELISA, FC, WB, Inhib, FuncS | Human IgG1 |
| HPAB-J0027-YC | Human Anti-ACVRL1 Recombinant Antibody (HPAB-J0027-YC) | ELISA | Human IgG |
| HPAB-J0028-YC | Human Anti-ACVRL1 Recombinant Antibody (HPAB-J0028-YC) | ELISA, FC, WB | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0024-YC-S(P) | Human Anti-ACVRL1 Recombinant Antibody; scFv Fragment (HPAB-J0024-YC-S(P)) | ELISA, FC, WB | Human scFv |
| HPAB-J0025-YC-S(P) | Human Anti-ACVRL1 Recombinant Antibody; scFv Fragment (HPAB-J0025-YC-S(P)) | ELISA, FC, WB | Human scFv |
| HPAB-J0026-YC-S(P) | Human Anti-ACVRL1 Recombinant Antibody; scFv Fragment (HPAB-J0026-YC-S(P)) | ELISA, FC, WB, Inhib, FuncS | Human scFv |
| HPAB-J0027-YC-S(P) | Human Anti-ACVRL1 Recombinant Antibody; scFv Fragment (HPAB-J0027-YC-S(P)) | ELISA | Human scFv |
| HPAB-J0028-YC-S(P) | Human Anti-ACVRL1 Recombinant Antibody; scFv Fragment (HPAB-J0028-YC-S(P)) | ELISA, FC, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY91 | Human Anti-ACVRL1 (clone MOR05377) scFv-Fc Chimera | ELISA, IHC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC491 | Recombinant Anti-ACVRL1 Vesicular Antibody, EV Displayed (VS-0425-YC491) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY141 | Anti-ACVRL1 Immunohistochemistry Kit | IHC |
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