Rabbit Anti-APOC3 Recombinant Antibody (clone R09-6C6) (CAT#: VS3-XY3263)
This is a recombinant rabbit antibody targeting the human Apolipoprotein C3 (APOC3), which plays a multifaceted role in triglyceride homeostasis. It has been reported for use in Western Blot and Immunohistochemistry-Paraffin. The recommended dilutions of western blot and Immunohistochemistry-Paraffin is 1/500-1/1000 and 1/50-1/100, respectively.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65365/1258_H7_2_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65365/1258_H7_2_selected.jpg
Figure 2 IHC staining of human liver
(Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_9_4_selected.jpg
(Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_9_4_selected.jpg
Figure 3 Small intestine
(Enterocytes Staining: Medium Intensity: Strong Quantity: <25% Enterocytes - Gradient Gradient: Ascending Enterocytes - Goblet cells Staining: Medium Intensity: Strong Quantity: <25% Paneth cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_4_2.jpg
(Enterocytes Staining: Medium Intensity: Strong Quantity: <25% Enterocytes - Gradient Gradient: Ascending Enterocytes - Goblet cells Staining: Medium Intensity: Strong Quantity: <25% Paneth cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_4_2.jpg
Figure 4 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_9_4.jpg
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_8_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_5_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_5_6.jpg
Figure 7 RNA cell line category: Group enriched (CACO-2, Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110245-APOC3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110245-APOC3
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human APOC3
- Species Reactivity
- Human
- Clone
- R09-6C6
- Applications
- WB, IHC-P
- Related Disease
- Apolipoprotein C-Iii Deficiency; Coronary Heart Disease 1
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
Target
- Alternative Names
- Apo-C3; ApoC-3; APOCIII
- Gene ID
- 345
- UniProt ID
- P02656
- Long Name
- Apolipoprotein C3
- Cellular Localization
- Chylomicron, Secreted
- Post Translation Modifications
- The most abundant glycoforms are characterized by an O-linked disaccharide galactose linked to N-acetylgalactosamine (Gal-GalNAc), further modified with up to 3 sialic acid residues. Less abundant glycoforms are characterized by more complex and fucosylated glycan moieties. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
- Protein Refseq
- NP_000031.1
- Function
- Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806).
Plays a multifaceted role in triglyceride homeostasis.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0952CLV | Human Anti-APOC3 Recombinant Antibody (TAB-0952CLV) | ELISA | Human IgG1 |
| TAB-0955CLV | Human Anti-APOC3 Recombinant Antibody (TAB-0955CLV) | ELISA | Human IgG |
| TAB-0956CLV | Human Anti-APOC3 Recombinant Antibody (TAB-0956CLV) | ELISA | Human IgG1 |
| TAB-0958CLV | Human Anti-APOC3 Recombinant Antibody (TAB-0958CLV) | ELISA | Human IgG1 |
| TAB-0960CLV | Human Anti-APOC3 Recombinant Antibody (TAB-0960CLV) | ELISA | Human IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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