Rabbit Anti-APOC3 Recombinant Antibody (clone R09-6C6)
CAT#: VS3-XY3263
This is a recombinant rabbit antibody targeting the human Apolipoprotein C3 (APOC3), which plays a multifaceted role in triglyceride homeostasis. It has been reported for use in Western Blot and Immunohistochemistry-Paraffin. The recommended dilutions of western blot and Immunohistochemistry-Paraffin is 1/500-1/1000 and 1/50-1/100, respectively.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/65365/1258_H7_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human liver
Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_9_4_selected.jpg
Normal Tissue
Figure 3 Small intestine
Enterocytes Staining: Medium Intensity: Strong Quantity: <25% Enterocytes - Gradient Gradient: Ascending Enterocytes - Goblet cells Staining: Medium Intensity: Strong Quantity: <25% Paneth cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_4_2.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73918/168345_A_5_6.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (CACO-2, Hep G2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110245-APOC3
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human APOC3
- Species Reactivity
- Human
- Clone
- R09-6C6
- Applications
- WB, IHC-P
- Related Disease
- Apolipoprotein C-Iii Deficiency; Coronary Heart Disease 1
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
Target
- Alternative Names
- Apo-C3; ApoC-3; APOCIII
- Gene ID
- 345
- UniProt ID
- P02656
- Long Name
- Apolipoprotein C3
- Cellular Localization
- Chylomicron, Secreted
- Post Translation Modifications
- The most abundant glycoforms are characterized by an O-linked disaccharide galactose linked to N-acetylgalactosamine (Gal-GalNAc), further modified with up to 3 sialic acid residues. Less abundant glycoforms are characterized by more complex and fucosylated glycan moieties. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
- Protein Refseq
- NP_000031.1
- Function
- Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806).
Plays a multifaceted role in triglyceride homeostasis.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "APOC3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0952CLV-F(E) | Human Anti-APOC3 Recombinant Antibody; Fab Fragment (TAB-0952CLV-F(E)) | ELISA | Human Fab |
| TAB-0955CLV-S(P) | Human Anti-APOC3 Recombinant Antibody; scFv Fragment (TAB-0955CLV-S(P)) | ELISA | Human scFv |
| TAB-0956CLV-S(P) | Human Anti-APOC3 Recombinant Antibody; scFv Fragment (TAB-0956CLV-S(P)) | ELISA | Human scFv |
| TAB-0958CLV-S(P) | Human Anti-APOC3 Recombinant Antibody; scFv Fragment (TAB-0958CLV-S(P)) | ELISA | Human scFv |
| TAB-0960CLV-S(P) | Human Anti-APOC3 Recombinant Antibody; scFv Fragment (TAB-0960CLV-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0213 | Hi-Affi™ Rabbit Anti-APOC3 Recombinant Antibody (clone DS213AB) | FC, IP, WB | Rabbit IgG |
| MOR-4533 | Hi-Affi™ Rabbit Anti-APOC3 Recombinant Antibody (clone TH41DS) | WB, IF, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1655-CN | Rabbit Anti-APOC3 Polyclonal Antibody (MRO-1655-CN) | WB, IHC, FC | Rabbit IgG |
| HPAB-N0018-YC | Human Anti-APOC3 Recombinant Antibody (HPAB-N0018-YC) | ELISA, FuncS | Human IgG1 |
| HPAB-N0019-YC | Human Anti-APOC3 Recombinant Antibody (HPAB-N0019-YC) | ELISA | Human IgG1 |
| HPAB-N0020-YC | Human Anti-APOC3 Recombinant Antibody (HPAB-N0020-YC) | ELISA | Human IgG1 |
| ZG-0547J | Rabbit Anti-APOC3 Recombinant Antibody (clone 8H12) | ELISA, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0018-YC-S(P) | Human Anti-APOC3 Recombinant Antibody; scFv Fragment (HPAB-N0018-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-N0019-YC-S(P) | Human Anti-APOC3 Recombinant Antibody; scFv Fragment (HPAB-N0019-YC-S(P)) | ELISA | Human scFv |
| HPAB-N0020-YC-S(P) | Human Anti-APOC3 Recombinant Antibody; scFv Fragment (HPAB-N0020-YC-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0018-YC-F(E) | Human Anti-APOC3 Recombinant Antibody; Fab Fragment (HPAB-N0018-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-N0019-YC-F(E) | Human Anti-APOC3 Recombinant Antibody; Fab Fragment (HPAB-N0019-YC-F(E)) | ELISA | Human Fab |
| HPAB-N0020-YC-F(E) | Human Anti-APOC3 Recombinant Antibody; Fab Fragment (HPAB-N0020-YC-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY459 | Anti-APOC3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY460 | Anti-Mouse APOC3 Immunohistochemistry Kit | IHC |
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