Rabbit Anti-APOC3 Recombinant Antibody (clone R09-6C6)

CAT#: VS3-XY3263

This is a recombinant rabbit antibody targeting the human Apolipoprotein C3 (APOC3), which plays a multifaceted role in triglyceride homeostasis. It has been reported for use in Western Blot and Immunohistochemistry-Paraffin. The recommended dilutions of western blot and Immunohistochemistry-Paraffin is 1/500-1/1000 and 1/50-1/100, respectively.

Gene Expression
Figure 1 IF staining of human cell line CACO-2 Figure 2 IHC staining of human liver Figure 3 Small intestine Figure 4 Liver Figure 5 Kidney Figure 6 Testis Figure 7 RNA cell line category: Group enriched (CACO-2, Hep G2)

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human APOC3
  • Species Reactivity
  • Human
  • Clone
  • R09-6C6
  • Applications
  • WB, IHC-P
  • Related Disease
  • Apolipoprotein C-Iii Deficiency; Coronary Heart Disease 1

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IHC: 1/50-1/100

Target

  • Alternative Names
  • Apo-C3; ApoC-3; APOCIII
  • Long Name
  • Apolipoprotein C3
  • Cellular Localization
  • Chylomicron, Secreted
  • Post Translation Modifications
  • The most abundant glycoforms are characterized by an O-linked disaccharide galactose linked to N-acetylgalactosamine (Gal-GalNAc), further modified with up to 3 sialic acid residues. Less abundant glycoforms are characterized by more complex and fucosylated glycan moieties. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
  • Function
  • Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806).
    Plays a multifaceted role in triglyceride homeostasis.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

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Isotype Control

Recommended Dilution Buffer

Secondary Antibody

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