Rabbit Anti-ARG1 Recombinant Antibody (VS3-CJ392)
CAT#: VS3-CJ392
This product is a rabbit antibody that recognizes ARG1.





Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat ARG1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IP
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunoprecipitation.
Target
- Alternative Names
- Arginase-1; Liver-type arginase; Type I arginase
- Gene ID
- 383
- UniProt ID
- P05089
- Sequence Similarities
- Belongs to the arginase family.
- Cellular Localization
- Cytoplasm
- Protein Refseq
- NP_000036.2; NP_001231367.1
- Function
- Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.
Functions in L-arginine homeostasis in nonhepatic tissues characterized by the competition between nitric oxide synthase (NOS) and arginase for the available intracellular substrate arginine. Arginine metabolism is a critical regulator of innate and adaptive immune responses. Involved in an antimicrobial effector pathway in polymorphonuclear granulocytes (PMN). Upon PMN cell death is liberated from the phagolysosome and depletes arginine in the microenvironment leading to suppressed T cell and natural killer (NK) cell proliferation and cytokine secretion (PubMed:15546957, PubMed:16709924, PubMed:19380772).
In group 2 innate lymphoid cells (ILC2s) promotes acute type 2 inflammation in the lung and is involved in optimal ILC2 proliferation but not survival (By similarity).
In humans, the immunological role in the monocytic/macrophage/dendritic cell (DC) lineage is unsure.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "ARG1"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0686MZ | Chicken Anti-ARG1 Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0238 | Hi-Affi™ Rabbit Anti-ARG1 Recombinant Antibody (clone DS238AB) | WB, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
VS3-CJ390 | Mouse Anti-ARG1 Recombinant Antibody (VS3-CJ390) | WB, IHC | Mouse IgG2b |
VS3-CJ391 | Mouse Anti-ARG1 Recombinant Antibody (VS3-CJ391) | IHC | Mouse IgG2a |
VS3-FY2627 | Mouse Anti-ARG1 Recombinant Antibody (VS3-FY2627) | WB, ICC, FC, ELISA | Mouse IgG |
VS7-HM132 | Mouse Anti-ARG1 Recombinant Antibody (clone 3A6A4) | WB, ICC, FCM | Mouse IgG2b |
VS7-HM133 | Mouse Anti-ARG1 Recombinant Antibody (clone 6B4B11) | IHC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0424-XY18 | AbPlus™ Anti-ARG1 Magnetic Beads (JB21-49) | IP, Protein Purification | |
VS-0724-YC1258 | AbPlus™ Anti-ARG1 Magnetic Beads (VS-0724-YC1258) | IP, Protein Purification |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0325-XY153 | Anti-ARG1 Immunohistochemistry Kit | IHC | |
VS-0525-XY498 | Anti-Mouse ARG1 Immunohistochemistry Kit | IHC | |
VS-0525-XY497 | Anti-Human ARG1 Immunohistochemistry Kit | IHC | |
VS-0525-XY499 | Anti-Rat ARG1 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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