Human Anti-B. burgdorferi OspA Recombinant Antibody (clone 3-24) (CAT#: FAMAB-0187JF)
Recombinant monoclonal antibody specially binds to outer surface protein A (OspA). This human anti-OspA antibody (3-24) can be a useful tool for analysis of the anti-OspA repertoire in patients and for identification of putative human mimics of the bacterial protein.
Specific Inquiry
IHC
Figure 1 Immunohistochemical analysis of reactivity of the generated anti-sera against neural tissue.
Bars=20 um.
Alaedini, A., & Latov, N. (2005). Antibodies against OspA epitopes of Borrelia burgdorferi cross-react with neural tissue. Journal of neuroimmunology, 159(1-2), 192-195.
WB
Figure 2 Immunological characterization (Western blot) of B. burgdorferi sensu lato strains with OspC-specific MAbs.
Molecular sizes are indicated on the left in kilodaltons.
Wilske, B., Jauris-Heipke, S., Lobentanzer, R., Pradel, I., Preac-Mursic, V., Rössler, D., ... & Johnson, R. C. (1995). Phenotypic analysis of outer surface protein C (OspC) of Borrelia burgdorferi sensu lato by monoclonal antibodies: relationship to genospecies and OspA serotype. Journal of clinical microbiology, 33(1), 103-109.
ELISA
Figure 3 Immunogenicities of OspA lipoprotein and nonlipoprotein.
Optical density at 490 nm.
Erdile, L. F., Brandt, M. A., Warakomski, D. J., Westrack, G. J., Sadziene, A., Barbour, A. G., & Mays, J. P. (1993). Role of attached lipid in immunogenicity of Borrelia burgdorferi OspA. Infection and immunity, 61(1), 81-90.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Borrelia burgdorferi OspA
- Species Reactivity
- B. burgdorferi
- Clone
- 3-24
- Applications
- WB, ELISA, IHC
- Related Disease
- Lyme disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The B. burgdorferi OspA antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
Fab Fragment Antibody
scFv Fragment Antibody
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-012 | Recombinant Mouse Anti-B. burgdorferi OspA Antibody (mAb184.1) | Neut | IgG |
| PABZ-012 | Recombinant Mouse Anti-B. burgdorferi OspA Antibody ( LA-2) | Neut, WB | IgG |
| MRO-017CQ | Recombinant Mouse Anti-B. burgdorferi OspA Antibody (0551) | ELISA, IF | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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