Human Anti-B. burgdorferi OspA Recombinant Antibody (clone 3-24) (CAT#: FAMAB-0187JF)

Recombinant monoclonal antibody specially binds to outer surface protein A (OspA). This human anti-OspA antibody (3-24) can be a useful tool for analysis of the anti-OspA repertoire in patients and for identification of putative human mimics of the bacterial protein.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA
IHC

Figure 1 Immunohistochemical analysis of reactivity of the generated anti-sera against neural tissue.

Figure 1 Immunohistochemical analysis of reactivity of the generated anti-sera against neural tissue.

Bars=20 um.

Alaedini, A., & Latov, N. (2005). Antibodies against OspA epitopes of Borrelia burgdorferi cross-react with neural tissue. Journal of neuroimmunology, 159(1-2), 192-195.

WB

Figure 2 Immunological characterization (Western blot) of B. burgdorferi sensu lato strains with OspC-specific MAbs.

Figure 2 Immunological characterization (Western blot) of B. burgdorferi sensu lato strains with OspC-specific MAbs.

Molecular sizes are indicated on the left in kilodaltons.

Wilske, B., Jauris-Heipke, S., Lobentanzer, R., Pradel, I., Preac-Mursic, V., Rössler, D., ... & Johnson, R. C. (1995). Phenotypic analysis of outer surface protein C (OspC) of Borrelia burgdorferi sensu lato by monoclonal antibodies: relationship to genospecies and OspA serotype. Journal of clinical microbiology, 33(1), 103-109.

ELISA

Figure 3 Immunogenicities of OspA lipoprotein and nonlipoprotein.

Figure 3 Immunogenicities of OspA lipoprotein and nonlipoprotein.

Optical density at 490 nm.

Erdile, L. F., Brandt, M. A., Warakomski, D. J., Westrack, G. J., Sadziene, A., Barbour, A. G., & Mays, J. P. (1993). Role of attached lipid in immunogenicity of Borrelia burgdorferi OspA. Infection and immunity, 61(1), 81-90.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • Borrelia burgdorferi OspA
  • Species Reactivity
  • B. burgdorferi
  • Clone
  • 3-24
  • Applications
  • WB, ELISA, IHC
  • Related Disease
  • Lyme disease

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The B. burgdorferi OspA antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry.

Target

  • Alternative Names
  • OspA outer surface protein A; OspA

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 3-24"

See other products for "B. burgdorferi OspA"

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for FAMAB-0187JF. Click the button above to contact us or submit your feedback about this product.

Popular products with customers


For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Go to compare

    Go to compare