Rabbit Anti-BANF1 Recombinant Antibody (clone R09-3F2) (CAT#: VS3-FY1621)
We demonstrated the assay in western blot analysis of BANF1 in Jurkat lysates. It is a amazing rabbit recombinant monoclonal antibody that is engineered to detect human BANF1. This R09-3F2 antibody is validated for western blot analysis of BANF1 in Jurkat lysates.
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WB
Figure 1 Anti-BANF1 Antibody (VS3-FY1621) in WB.
The BANF1 expression in Jurkat lysates were detected using the anti-BANF1 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human BANF1
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human BANF1
- Species Reactivity
- Human
- Clone
- R09-3F2
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 10 kDa, while the observed molecular weight stands at 10 kDa.
- Related Disease
- Nestor-Guillermo Progeria Syndrome and Vaccinia
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Barrier To Autointegration Factor 1; Breakpoint Cluster Region Protein 1; BAF; Barrier-To-Autointegration Factor; D14S1460; BCRP1; BCRG1; NGPS
- Gene ID
- 8815
- UniProt ID
- O75531
- Sequence Similarities
- Belongs to the BAF family.
- Cellular Localization
- Chromosome, Cytoplasm, Nucleus
- Post Translation Modifications
- Acetylation, Phosphoprotein
- Protein Refseq
- NP_001137457.1; NP_003851.1
- Function
- Non-specific DNA-binding protein that plays key roles in mitotic nuclear reassembly, chromatin organization, DNA damage response, gene expression and intrinsic immunity against foreign DNA.
Contains two non-specific double-stranded DNA (dsDNA)-binding sites which promote DNA cross-bridging.
Plays a key role in nuclear membrane reformation at the end of mitosis by driving formation of a single nucleus in a spindle-independent manner.
Transiently cross-bridges anaphase chromosomes via its ability to bridge distant DNA sites, leading to the formation of a dense chromatin network at the chromosome ensemble surface that limits membranes to the surface.
Also acts as a negative regulator of innate immune activation by restricting CGAS activity toward self-DNA upon acute loss of nuclear membrane integrity.
Outcompetes CGAS for DNA-binding, thereby preventing CGAS activation and subsequent damaging autoinflammatory responses.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "BANF1"
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0463MZ | Mouse Anti-BANF1 Recombinant Antibody (clone CBLS-035) | IF, IHC-P, WB | Mouse IgG2a |
| MRO-0153-CN | Rabbit Anti-BANF1 Recombinant Antibody (clone JG40-43) | WB, IF, IHC, FC | Rabbit IgG |
| VS13-YC87 | Rabbit Anti-BANF1 Recombinant Antibody (VS13-YC87) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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