Afuco™ Anti-C. difficile toxin B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-725) (CAT#: AFC-TAB-725)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant human monoclonal antibody expressed in CHO binding to toxin B [C. difficile]. It is a human monoclonal antibody designed for the prevention of recurrence of Clostridium difficile infection.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • C. difficile
  • Applications
  • FC, IP, ELISA, Neut, FuncS
  • Conjugate
  • Unconjugated
  • Generic Name
  • Bezlotoxumab
  • Related Disease
  • Clostridium difficileinfectious diarrhea

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • C. difficile Toxin B; Clostridium difficile Toxin B; Cytotoxin B; tcdB; toxB; Toxin B

Related Resources

  • Biosimilar Overview
Please refer to Bezlotoxumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Bezlotoxumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Anti-C. Diff Toxin B Recombinant Antibody (Bezlotoxumab)
Recombinant human monoclonal antibody expressed in CHO binding to toxin B [C. difficile]. Bezlotoxumab is a human monoclonal antibody designed for the prevention of recurrence of Clostridium difficile infection.
DrugMonitor™ Anti-Bezlotoxumab Antibody (VS-1224-YC191)
Bezlotoxumab is a fully humanized IgG1 kappa monoclonal antibody that binds to and neutralizes Clostridium difficile toxin B, used to reduce C. difficile infection recurrence. The DrugMonitor™ Anti-Bezlotoxumab Antibody (VS-1224-YC191) is an anti-drug antibody (ADA) against Bezlotoxumab. This drug-based antibody is raised in mice immunized with the Bezlotoxumab. The anti-Bezlotoxumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Bezlotoxumab in samples.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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