AbPlus™ Anti-CANX Magnetic Beads (CGMCCNo.3240)
CAT#: VS-0424-XY40
The AbPlus Anti-CANX Magnetic Beads (CGMCCNo.3240) is an innovative affinity resin which is bound with anti-CANX specific antibody (CGMCCNo.3240). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CANX protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9433/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4738/11907_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75% Mucosal lymphoid cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4738/11907_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4738/11907_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4738/11907_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Low Intensity: Weak Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4738/11907_A_6_6.jpg
Normal Tissue
Figure 7 Skin
Cells in basal layer Staining: Medium Intensity: Moderate Quantity: 75%-25% Cells in granular layer Staining: Medium Intensity: Moderate Quantity: 75%-25% Cells in spinous layer Staining: Medium Intensity: Moderate Quantity: 75%-25% Endothelial cells Staining: High Intensity: Strong Fibrohistiocytic cells Staining: High Intensity: Strong Langerhans cells Staining: High Intensity: Strong Quantity: 75%-25% Lymphocytes Staining: High Intensity: Strong Melanocytes Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4738/11907_B_8_1.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4738/11907_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (hTERT-HME1, SK-MEL-30)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000127022-CANX
❮
❯
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-CANX specific antibody (CGMCCNo.3240)
- Target
- CANX
- Immunogen
- Supernant of the lysate of MCF-7 cells
- Target Species
- Human
- Antibody Clone
- CGMCCNo.3240
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
- Alternative Names
- Calnexin; Major Histocompatibility Complex Class I Antigen-Binding Protein P88 2; IP90; P90; CNX
- Gene ID
- 821
- UniProt ID
- P27824
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "CANX"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0551MZ | Mouse Anti-CANX Recombinant Antibody (clone 7G23CF20) | FC, ICC, IP, ELISA | Mouse IgG2b |
| MRO-1711-CN | Rabbit Anti-CANX Polyclonal Antibody (MRO-1711-CN) | WB, IHC, FC | Rabbit IgG |
| ZG-0358F | Mouse Anti-CANX Recombinant Antibody (ZG-0358F) | WB, IF, ELISA | Mouse IgG |
| VS3-CJ841 | Rabbit Anti-CANX Recombinant Antibody (VS3-CJ841) | WB, ICC, IF, IHC, FC | Rabbit IgG |
| VS7-HM289 | Mouse Anti-CANX Recombinant Antibody (clone CBL094HM) | WB, IF, ICC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0456 | Hi-Affi™ Rabbit Anti-CANX Recombinant Antibody (clone DS456AB) | IHC-P, IP, WB | Rabbit IgG |
| MOR-0079-FY | Rabbit Anti-CANX Recombinant Antibody (clone AFY0050) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-013CN | Mouse Anti-CANX Recombinant Antibody (clone CGMCCNo.3240) | ELISA, WB, IHC, IP, IF | Mouse IgG2b |
| NS-013CN-F(E) | Mouse Anti-CANX Recombinant Antibody (clone CGMCCNo.3240); Fab Fragment | ELISA, WB, IHC, IP, IF | Mouse Fab |
| NS-013CN-S(P) | Mouse Anti-CANX Recombinant Antibody (clone CGMCCNo.3240); scFv Fragment | ELISA, WB, IHC, IP, IF | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC826 | AbPlus™ Anti-CANX Magnetic Beads (VS-0724-YC826) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY304 | Anti-CANX Immunohistochemistry Kit | IHC | |
| VS-0525-XY968 | Anti-Mouse CANX Immunohistochemistry Kit | IHC | |
| VS-0525-XY967 | Anti-Human CANX Immunohistochemistry Kit | IHC | |
| VS-0525-XY969 | Anti-Canine CANX Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC117 | CytoStream™ Rabbit Anti-CANX Recombinant Antibody (VS13-YC117) | WB, ICC, IF, IHC-P, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC443 | Recombinant Anti-CANX Vesicular Antibody, EV Displayed (VS-0425-YC443) | ELISA, FC, Cell-uptake |
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