CytoStream™ Rabbit Anti-CANX Recombinant Antibody (VS13-YC117) (CAT#: VS13-YC117)

• Immunogen
• Recombinant human Calnexin, aa 543-592.

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human and Rat CANX

• Species Reactivity
• Human, Rat

• Applications
• WB, ICC, IF, IHC-P, FC

• Conjugate
• NONE

• Clonality
• Monoclonal

• Purification
• Protein A purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.

• Preservative
• 0.05% Sodium azide

• Storage
• Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Shipping with ice pack.

• Application Notes
• Western blot (WB): 1/1000-1/5000
  Immunocytochemistry (ICC): 1/100-1/500
  Immunofluorescence (IF): 1/100-1/500
  Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
  Flow cytometry (FC): 1/50-1/100

• Alternative Names
• Calnexin; Major Histocompatibility Complex Class I Antigen-Binding Protein P88; IP90; P90; CNX;

• Gene ID
• 821

• UniProt ID
• P27824

• Long Name
• Calnexin

• Sequence Similarities
• Belongs to the calreticulin family.

• Cellular Localization
• Endoplasmic reticulum membrane; Endoplasmic reticulum; Melanosome

• Protein Refseq
• NP_001019820.1; NP_001737.1

• Function
• Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-061CQ
• Sheep Anti-Rabbit IgG (H&L) Antibody

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

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