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    Rabbit Anti-CASP10 Recombinant Antibody (VS3-WK1582) (CAT#: VS3-WK1582)

    This antibody is a rabbit recombinant antibody against human CASP10, which is a member of the cysteine-aspartic acid protease (caspase) family. This clone can be used in WB analysis at a dilution of 1/500-2000 and in ELISA analysis at a dilution of 1/5000-20000.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line Hep G2
    Figure 1 IF staining of human cell line Hep G2
    (Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/1404_C2_1_selected.jpg
    Normal Tissue
    Figure 2 Lymph node
    Figure 2 Lymph node
    (Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_7_8.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_7_3.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_7_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_5_6.jpg
    RNA Expression
    Figure 6 RNA cell line category: Cell line enhanced (HUVEC TERT2)
    Figure 6 RNA cell line category: Cell line enhanced (HUVEC TERT2)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000003400-CASP10

    Specifications

    • Immunogen
    • Synthesized peptide derived from human Caspase 10 (p23/17, Cleaved-Val220)
    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human CASP10
    • Species Reactivity
    • Human, Mouse, Rat
    • Applications
    • WB, ELISA
    • Conjugate
    • Unconjugated

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A affinity purified
    • Purity
    • >95% as determined by SDS-PAGE
    • Aggregation
    • < 5%
    • Format
    • Liquid
    • Concentration
    • 1 mg/mL
    • Buffer
    • PBS, 0.5% BSA, 50% Glycerol
    • Preservative
    • 0.02% Sodium Azide
    • Storage
    • Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • WB: 1/500-1/2000
      ELISA: 1/5000-1/20000

    Target

    • Alternative Names
    • Caspase 10; FAS-Associated Death Domain Protein Interleukin-1B-Converting Enzyme 2; Caspase 10, Apoptosis-Related Cysteine Protease; ICE-Like Apoptotic Protease 4; CASP-10; FLICE2; MCH4; Caspase 10, Apoptosis-Related Cysteine Peptidase; Caspase 10 Apoptosis-Related Cysteine Peptidase
    • Long Name
    • Caspase 10
    • Sequence Similarities
    • Belongs to the peptidase C14A family.
    • Cellular Localization
    • Cytoplasm, Cytosol, Ripoptosome
    • Post Translation Modifications
    • Cleavage by granzyme B and autocatalytic activity generate the two active subunits.
    • Function
    • Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways.

    Recommended Products

    Secondary Antibody

    Isotype Control

    Related Resources

    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "CASP10"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Rabbit Monoclonal Antibody Products Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
    CAT Product Name Application Type
    MOB-2489z Mouse Anti-CASP10 Recombinant Antibody (clone 42G5) WB, ELISA, IF, IP Mouse IgM, κ
    MOB-0324CT Mouse Anti-CASP10 Recombinant Antibody (clone 3F8) ELISA, WB Mouse IgG2a
    MRO-0238-CN Rabbit Anti-CASP10 Recombinant Antibody (clone CBACN-087) WB, IHC, IP, FC Rabbit IgG
    VS3-WK1089 Rabbit Anti-CASP10 Recombinant Antibody (VS3-WK1089) WB, IHC, IP, FC Rabbit IgG
    VS3-XY3288 Rabbit Anti-CASP10 Recombinant Antibody (clone R03-3B2) WB, IHC-P, ICC, IF, IP, FC Rabbit IgG

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