Rabbit Anti-CASP10 Recombinant Antibody (VS3-WK1582) (CAT#: VS3-WK1582)
This antibody is a rabbit recombinant antibody against human CASP10, which is a member of the cysteine-aspartic acid protease (caspase) family. This clone can be used in WB analysis at a dilution of 1/500-2000 and in ELISA analysis at a dilution of 1/5000-20000.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/1404_C2_1_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/1404_C2_1_selected.jpg
Figure 2 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_7_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_7_8.jpg
Figure 3 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_7_3.jpg
Figure 4 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_7_5.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_5_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17059/40550_A_5_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (HUVEC TERT2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000003400-CASP10
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000003400-CASP10
Specifications
- Immunogen
- Synthesized peptide derived from human Caspase 10 (p23/17, Cleaved-Val220)
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CASP10
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 0.5% BSA, 50% Glycerol
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/2000
ELISA: 1/5000-1/20000
Target
- Alternative Names
- Caspase 10; FAS-Associated Death Domain Protein Interleukin-1B-Converting Enzyme 2; Caspase 10, Apoptosis-Related Cysteine Protease; ICE-Like Apoptotic Protease 4; CASP-10; FLICE2; MCH4; Caspase 10, Apoptosis-Related Cysteine Peptidase; Caspase 10 Apoptosis-Related Cysteine Peptidase
- Gene ID
- 843
- UniProt ID
- Q92851
- Long Name
- Caspase 10
- Sequence Similarities
- Belongs to the peptidase C14A family.
- Cellular Localization
- Cytoplasm, Cytosol, Ripoptosome
- Post Translation Modifications
- Cleavage by granzyme B and autocatalytic activity generate the two active subunits.
- Protein Refseq
- NP_001193453.1
- Function
- Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways.
Recommended Products
Secondary Antibody
Isotype Control
Related Resources
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2489z | Mouse Anti-CASP10 Recombinant Antibody (clone 42G5) | WB, ELISA, IF, IP | Mouse IgM, κ |
| MOB-0324CT | Mouse Anti-CASP10 Recombinant Antibody (clone 3F8) | ELISA, WB | Mouse IgG2a |
| MRO-0238-CN | Rabbit Anti-CASP10 Recombinant Antibody (clone CBACN-087) | WB, IHC, IP, FC | Rabbit IgG |
| VS3-WK1089 | Rabbit Anti-CASP10 Recombinant Antibody (VS3-WK1089) | WB, IHC, IP, FC | Rabbit IgG |
| VS3-XY3288 | Rabbit Anti-CASP10 Recombinant Antibody (clone R03-3B2) | WB, IHC-P, ICC, IF, IP, FC | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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