Rabbit Anti-CD207 Recombinant Antibody (clone R01-6X3)

CAT#: VS3-XY3294

It is a recombinant rabbit antibody that recognizes human CD207 molecule (CD207), which induces the formation of Birbeck granules (BGs). The antibody recognizes and binds to human CD207. This antibody has been used in Immunohistochemistry-Paraffin. The recommended dilutions of Immunohistochemistry-Paraffin is 1/50-1/100.

Gene Expression
Figure 1 IF staining of human cell line HAP1 Figure 2 Skin Figure 3 Lymph node Figure 4 RNA cell line category: Cell line enriched (AN3-CA)

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human CD207
  • Species Reactivity
  • Human
  • Clone
  • R01-6X3
  • Related Disease
  • Birbeck granule deficiency (BIRGD)

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • IHC: 1/50-1/100

Target

  • Alternative Names
  • CLEC4K
  • Long Name
  • CD207 molecule
  • Cellular Localization
  • Membrane
  • Post Translation Modifications
  • Glycosylation at Asn87, Asn113, and Asn180 (NX_Q9UJ71 [NX_Q9UJ71-1])
    Modification sites at PhosphoSitePlus (Q9UJ71)
    Glycosylation from GlyGen (Q9UJ71) 3 sites
  • Function
  • Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

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Isotype Control

Recommended Dilution Buffer

Secondary Antibody

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