Rabbit Anti-CD207 Recombinant Antibody (clone R01-6X3) (CAT#: VS3-XY3294)
It is a recombinant rabbit antibody that recognizes human CD207 molecule (CD207), which induces the formation of Birbeck granules (BGs). The antibody recognizes and binds to human CD207. This antibody has been used in Immunohistochemistry-Paraffin. The recommended dilutions of Immunohistochemistry-Paraffin is 1/50-1/100.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HAP1
(Immunofluorescent staining of human cell line HAP1 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/1973_E10_5_cr5de7b118a3d6b_selected.jpg
(Immunofluorescent staining of human cell line HAP1 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/1973_E10_5_cr5de7b118a3d6b_selected.jpg
Figure 2 Skin
(Langerhans
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/27981_B_7_1.jpg
(Langerhans
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/27981_B_7_1.jpg
Figure 3 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/27981_A_9_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11216/27981_A_9_8.jpg
Figure 4 RNA cell line category: Cell line enriched (AN3-CA)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000116031-CD207
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000116031-CD207
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CD207
- Species Reactivity
- Human
- Clone
- R01-6X3
- Applications
- IHC-P
- Related Disease
- Birbeck granule deficiency (BIRGD)
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- IHC: 1/50-1/100
Target
- Alternative Names
- CLEC4K
- Gene ID
- 50489
- UniProt ID
- Q9UJ71
- Long Name
- CD207 molecule
- Cellular Localization
- Membrane
- Post Translation Modifications
- Glycosylation at Asn87, Asn113, and Asn180 (NX_Q9UJ71 [NX_Q9UJ71-1])
Modification sites at PhosphoSitePlus (Q9UJ71)
Glycosylation from GlyGen (Q9UJ71) 3 sites
- Protein Refseq
- XP_011531177.1
- Function
- Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-169 | Recombinant Anti-human CD207 Antibody | ELISA, WB, FC, FuncS | IgG |
| MHH-169 | Recombinant Human Anti-human CD207 Antibody | WB, FC, FuncS | IgG |
| HPAB-AP027-YC | Mouse Anti-CD207 Recombinant Antibody (HPAB-AP027-YC) | ELISA, FC | Mouse IgG |
| HPAB-AP028-YC | Mouse Anti-CD207 Recombinant Antibody (HPAB-AP028-YC) | ELISA, FC | Mouse IgG |
| HPAB-AP029-YC | Mouse Anti-CD207 Recombinant Antibody (HPAB-AP029-YC) | ELISA, FC | Mouse IgG2a, κ |
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