This product is a recombinant antibody that recognizes CD58. The monoclonal antibody 1E6 reacts with the epitope of CD58.
Figure 1 mAb IE6, reactive with LFA-3, reduced the secretion of IL-2 and IFN-γ from both naive and memory CD41 T cells that were costimulated by either ECs or PBAMCs.
mAb to LFA-3 (IE6) was added to: cocultures of naive CD41 T cells. Cytokines were measured by ELISA after 24 h.
Ma, W. , & Pober, J. S. . (1998). Human endothelial cells effectively costimulate cytokine production by, but not differentiation of, naive cd4+ t cells. The Journal of Immunology, 161(5), 2158-2167.
Figure 2 mAb IE6, reactive with LFA-3, reduced the secretion of IL-2 and IFN-γ from both naive and memory CD41 T cells that were costimulated by either ECs or PBAMCs.
mAb to LFA-3 (IE6) was added to: cocultures of memory CD41 T cells. Cytokines were measured by ELISA after 24 h.
Ma, W. , & Pober, J. S. . (1998). Human endothelial cells effectively costimulate cytokine production by, but not differentiation of, naive cd4+ t cells. The Journal of Immunology, 161(5), 2158-2167.
Figure 3 Depicts results of immunofluorescence flow cytometry by FACS analysis of SRBCs exposed to buffer (solid lines) or to anti-LFA-3 antibodies (dashed lines) 1E6.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1415z | Mouse Anti-CD58 Recombinant Antibody (clone 40C4) | WB, IP, FC | Mouse IgG1 |
MOB-0052MZ | Recombinant Mouse Anti-Human CD58 Antibody (clone NEM-64) | FC, IP, WB | Mouse antibody |
FN-063CQ | Mouse Anti-CD58 Recombinant Antibody (clone TS2) | FC, FuncS | Mouse IgG1 |
VS2-QX19 | Mouse Anti-CD58 Recombinant Antibody (clone BRIC 5) | IB | Mouse IgG2a, κ |
VS3-WK1490 | Mouse Anti-CD58 Recombinant Antibody (clone S112) | FC, IF | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-396CQ | Mouse Anti-CD58 Recombinant Antibody (clone TS2/9) | Block, ELISA, FC, ICC, IF, IHC, IHC-Fr, IP, Neut, WB | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0571 | Hi-Affi™ Rabbit Anti-CD58 Recombinant Antibody (clone DS571AB) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1837-FY-F(E) | Mouse Anti-CD58 Recombinant Antibody (clone 1E6); scFv Fragment | FC, Inhib | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1837-FY-S(P) | Mouse Anti-CD58 Recombinant Antibody (clone 1E6); Fab Fragment | FC, Inhib | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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