AbPlus™ Anti-CDH11 Magnetic Beads (16A6) (CAT#: VS-0424-XY59)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-CDH11 specific antibody (16A6)

• Target
• CDH11

• Immunogen
• Extracellular domain of human CDH11 fused to maltose binding protein

• Target Species
• Human

• Antibody Clone
• 16A6

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

• Alternative Names
• OB; ESWS; CAD11; CDHOB; OSF-4; TBHS2; cadherin-11; cadherin 11, type 2, OB-cadherin (osteoblast)

• Gene ID
• 1009

• UniProt ID
• P55287

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