CytoStream™ Rabbit Anti-CDK5 Recombinant Antibody (VS13-YC199) (CAT#: VS13-YC199)

Name: CytoStream™ Rabbit Anti-CDK5 Recombinant Antibody (VS13-YC199)
SKU: VS13-YC199
Rating: 5 (1 reviews)

The CytoStream™ Rabbit Anti-CDK5 Recombinant Antibody is specific for human, mouse and rat CDK5. CDK5 participates in neurological development and disorders, exemplifying roles in kinase-related signaling pathways. The anti-CDK5 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50).

Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

We require custom production

Gene Expression
Datasheet
MSDS
COA

Subcellular Location

Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64535/1202_C5_1_selected.jpg

Normal Tissue

Figure 2 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: Low Intensity: Weak Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8909/22984_A_6_6.jpg

Figure 3 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8909/22984_A_8_8.jpg

Figure 4 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8909/22984_B_8_5.jpg

Figure 5 Caudate
(Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8909/22984_B_9_7.jpg

Figure 6 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8909/22984_A_7_3.jpg

RNA Expression

Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164885-CDK5

Datasheet

MSDS

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Immunogen
Recombinant human Cdk5, aa 243-292.

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human, Mouse and Rat CDK5

Species Reactivity
Human, Mouse, Rat

Applications
WB, IHC-P, FC, IP

Conjugate
NONE

Related Disease
Lissencephaly 7 With Cerebellar Hypoplasia and Lissencephaly

Product Property

Clonality
Monoclonal

Purification
Protein A purified

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Buffer
TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.

Preservative
0.05% Sodium azide

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Shipping
Shipping with ice pack.

Applications

Application Notes
Western blot (WB): 1/500
Immunohistochemistry-paraffin (IHC-P): 1/50-1/400
Flow cytometry (FC): 1/50

Target

Alternative Names
Cyclin Dependent Kinase 5; Serine/Threonine-Protein Kinase PSSALRE; Tau Protein Kinase II Catalytic Subunit; Cell Division Protein Kinase 5; TPKII Catalytic Subunit; Cyclin-Dependent-Like Kinase 5; Protein Kinase CDK5 Splicing;

Gene ID
1020

UniProt ID
Q00535

Long Name
Cyclin Dependent Kinase 5

Cellular Localization
Cell membrane; Cell projection; Cytoplasm; Nucleus; Synapse

Protein Refseq
NP_004926.1; NP_001157882.1

Function
Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins.

Secondary Antibody

Isotype Control

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CDK5"

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Please select product type

IgG Antibody Products Rabbit Monoclonal Antibody Products Non-Human Primate (NHP) Antibody Products IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry

CAT	Product Name	Application	Type
MOB-0162CT	Recombinant Mouse anti-Human CDK5 Monoclonal antibody (5F5)	ELISA, FC, ICC/IF, IHC-P, WB
VS3-XY476	Mouse Anti-CDK5 Recombinant Antibody (clone 1321CT281.130.129)	WB
VS3-WK833	Mouse Anti-CDK5 Recombinant Antibody (VS3-WK833)	WB	Mouse IgG1, κ
VS3-WK834	Rabbit Anti-CDK5 Recombinant Antibody (VS3-WK834)	WB, IHC, IP, FC	Rabbit IgG
VS3-XY3307	Rabbit Anti-CDK5 Recombinant Antibody (clone R08-9I3)	WB, IHC-P, IP, FC	Rabbit IgG

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