Mouse Anti-CDKN1C Recombinant Antibody (clone ABT-P57)
CAT#: VS3-CJ1002
This product is a mouse antibody that recognizes human CDKN1C.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, nuclear bodies & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/32_C5_1_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_B_8_5.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Collecting ducts Staining: Medium Intensity: Strong Quantity: <25% Distal tubules Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_A_4_6.jpg
Normal Tissue
Figure 5 Placenta
Decidual cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Trophoblastic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2924/155493_A_1_7.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (EFO-21, HeLa, RPMI-8226, SH-SY5Y, SiHa, SK-MEL-30)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000129757-CDKN1C
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Specifications
- Immunogen
- Synthesized peptide derived from human p57kip2
- Host Species
- Mouse
- Type
- Mouse IgG2a, κ
- Specificity
- Human CDKN1C
- Species Reactivity
- Human
- Clone
- ABT-P57
- Applications
- IHC-P
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity Chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.5% BSA, PBS.
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Immunohistochemistry-Parraffin (1:100-1:500).
Target
- Alternative Names
- BWS; WBS; p57; BWCR; KIP2; p57Kip2
- Gene ID
- 1028
- UniProt ID
- P49918
- Sequence Similarities
- Belongs to the CDI family.
- Cellular Localization
- Nucleus
- Protein Refseq
- NP_000067.1; NP_001116102.1; NP_001116103.1
- Function
- Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "CDKN1C"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1514CT | Recombinant Mouse anti-Human CDKN1C Monoclonal antibody (4F4) | ELISA, WB | |
| VS3-CJ1003 | Mouse Anti-CDKN1C Recombinant Antibody (clone PT0208) | IHC-P | Mouse IgG3, κ |
| VS3-FY356 | Recombinant Mouse Anti-CDKN1C Antibody (clone 1F4A9) | ELISA, WB, IHC, FC | Mouse IgG1 |
| VS3-FY357 | Recombinant Mouse Anti-CDKN1C Antibody (clone 8G5D5) | ELISA, WB, IHC, FC | Mouse IgG1 |
| VS3-FY358 | Recombinant Mouse Anti-CDKN1C Antibody (clone 7H9-2G7-5G5) | IHC-P | Mouse IgG3 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0641 | Hi-Affi™ Rabbit Anti-CDKN1C Recombinant Antibody (clone DS641AB) | WB, IP, IHC-P, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX221 | Mouse Anti-CDKN1C Recombinant Antibody (clone 522CT9.5.1) | WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY413 | Anti-CDKN1C Immunohistochemistry Kit | IHC | |
| VS-0525-XY1338 | Anti-Mouse CDKN1C Immunohistochemistry Kit | IHC | |
| VS-0525-XY1337 | Anti-Human CDKN1C Immunohistochemistry Kit | IHC |
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