Mouse Anti-CFH Recombinant Antibody (clone OX23) (CAT#: FAMAB-1105CQ)

This product is a recombinant mouse antibody that recognizes CFH. The antibody was purified by affinity chromatography. It can be used in IP, WB, Block, ELISA.

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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
IF

Figure 1 Endogenous CFH associates with GAGs in Bruch’s membrane and RPE within human macula.

Figure 1 Endogenous CFH associates with GAGs in Bruch’s membrane and RPE within human macula.

Endogenous CFH was detected (using OX23 monoclonal antibodies and the appropriate Alexa Fluor 488-labeled secondary antibody) in human eye sections from five heterozygous individuals either untreated or following treatment with Heparinase and chondroitinase B.

Clark, S. J., Perveen, R., Hakobyan, S., Morgan, B. P., Sim, R. B., Bishop, P. N., & Day, A. J. (2010). Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina. Journal of Biological Chemistry, 285(39), 30192-30202.


Specifications

  • Immunogen
  • Native protein purified from plasma
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Factor H
  • Species Reactivity
  • Primate, Human, Mouse
  • Clone
  • OX23
  • Applications
  • IF

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Immunofluorescence.

Target

  • Alternative Names
  • Complement Factor H; Age-Related Maculopathy Susceptibility 1; H Factor 2 (Complement); H Factor 1 (Complement); Beta-1H; HF1; HF2; HF; Adrenomedullin Binding Protein; Beta-1-H-Globulin; Factor H-Like 1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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comprehensive guidelines
The comprehensive instructions that came with this product have been very beneficial in assuring correct use and optimizing its efficacy.

Reliable performance
Every batch of this product has continuously delivered exceptional performance, which is essential for our long-term projects.

Detailed protocols provided
The antibody was provided with complete methods that really aided in directing our investigation. They assured that we received the best results by reviewing a number of applications and troubleshooting strategies.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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