AibGenesis™ Rabbit Anti-CIRBP Recombinant Antibody (AibG-Rb-CI335)
CAT#: VS-0426-FY335
Established via our AI-powered antibody discovery platform, this Rabbit IgG targets CIRBP. Validated for WB and IP in Mouse and Rat, it provides a highly specific reagent for researchers studying cold-shock proteins and the cellular response to hypothermia and environmental stress.
Specifications
- Immunogen
- Mouse
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Mouse CIRBP
- Species Reactivity
- Mouse, Rat
- Clone
- AibG-Rb-CI335
- Applications
- Western Blot, Immunoprecipitation
- Conjugate
- Unconjugated, Biotin and FITC are available.
- Related Disease
- Hypothermia-induced Cellular Stress
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% Glycerol, 0.05% Protective protein
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (1:500-1:2000), Immunoprecipitation (1:20-1:50)
Target
- Alternative Names
- Cirp
- Gene ID
- 12696
- UniProt ID
- P60824
- Long Name
- Cold Inducible RNA Binding Protein
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Methylated on arginine residues. Methylation of the RGG motifs is a prerequisite for recruitment into SGs.
Phosphorylated by CK2, GSK3A and GSK3B. Phosphorylation by GSK3B increases RNA-binding activity to the TXN 3'-UTR transcript upon exposure to UV radiation.
- Protein Refseq
- XP_006722700.1; XP_011525970.1; XP_016881726.1; XP_054175689.1; XP_054175690.1
- Function
- Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "CIRBP"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY1687 | Rabbit Anti-CIRBP Recombinant Antibody (clone R01-4B2) | WB, IHC-P, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS7-HM737 | Mouse Anti-CIRBP Recombinant Antibody (clone 6E12D5) | IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS7-HM738 | Mouse Anti-CIRBP Recombinant Antibody (clone 6E12B3) | WB, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY457 | Anti-CIRBP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1464 | Anti-Human CIRBP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0326-YC659 | Mouse Anti-CIRBP Recombinant Antibody (CI659) | ELISA, WB, IHC | Mouse IgG1 |
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