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Mouse Anti-CLDN3 Recombinant Antibody (clone ABT-CLD3) (CAT#: VS3-CJ143)

This product is a mouse antibody that recognizes CLDN3.


See more Engineered Antibody products for CLDN3
Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line MCF7
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/1661_D5_4_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_B_8_5.jpg
Figure 3 Small intestine
Figure 3 Small intestine
(Endocrine cells
Staining:High
Intensity: Strong
Enterocytes
Staining:High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining:High
Intensity: Strong
Goblet cells
Staining:High
Intensity: Strong
Quantity:>75%
Paneth cells
Staining:High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_4_2.jpg
Figure 4 Colon
Figure 4 Colon
(Endocrine cells
Staining:High
Intensity: Strong
Enterocytes
Staining:High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining:High
Intensity: Strong
Goblet cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_7_3.jpg
Figure 5 Liver
Figure 5 Liver
(Cholangiocytes
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_8_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%
Collecting ducts
Staining:High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining:High
Intensity: Strong
Quantity:>75%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_9_5.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (MCF7, PC-3, RPMI-8226, SCLC-21H, T-47d)
Figure 7 RNA cell line category: Cell line enhanced (MCF7, PC-3, RPMI-8226, SCLC-21H, T-47d)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000165215-CLDN3

Specifications

  • Immunogen
  • Synthesized peptide derived from human Claudin 3
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1, κ
  • Specificity
  • Human CLDN3
  • Species Reactivity
  • Human
  • Clone
  • ABT-CLD3
  • Applications
  • WB, IHC
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Affinity chromatography
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Buffer
  • 50% Glycerol, 0.5% BSA, PBS.
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • This antibody has been tested for use in Western Blot (1:500-1:2000), Immunohistochemistry-Parraffin (1:100-1:500).

Target

  • Alternative Names
  • C7orf1; CPETR2; Claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2; Rat ventral prostate.1 protein homolog; Hrvp1; RVP1
  • Sequence Similarities
  • Belongs to the claudin family.
  • Cellular Localization
  • Cell junction, Cell membrane, Membrane, Tight junction
  • Function
  • Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Recommended Products

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CLDN3"

Single-domain Antibody

CAT Product Name Application Type
NAB-610-VHH Recombinant Anti-Human CLDN3 VHH Single Domain Antibody ELISA, Neut, ICC, FC Llama VHH

Recombinant Antibody

CAT Product Name Application Type
MOB-2321z Mouse Anti-CLDN3 Recombinant Antibody (clone 4B11) WB, IHC Mouse IgG2b
VS3-CJ144 Mouse Anti-CLDN3 Recombinant Antibody (clone PT1687) IHC-P Mouse IgG1, κ
VS3-CJ145 Mouse Anti-CLDN3 Recombinant Antibody (VS3-CJ145) WB, IHC Mouse IgG1
VS3-FY390 Recombinant Mouse Anti-CLDN3 Antibody (clone 10F10-3E3-8G5) IHC-P Mouse IgG1
VS3-FY391 Recombinant Rabbit Anti-CLDN3 Antibody (clone R08-4F8) WB, ICC, IF, IP Rabbit IgG

Chimeric Antibody

CAT Product Name Application Type
TAB-495LC Anti-Human CLDN3 Recombinant Antibody (Chimeric CDN04) Cyt, FC, Inhib Chimeric antibody (mouse/human)
TAB-496LC Anti-Human CLDN3 Recombinant Antibody (Chimeric CDN16) Cyt, FC, Inhib Chimeric antibody (mouse/human)
TAB-497LC Anti-Human CLDN3 Recombinant Antibody (Chimeric CDN27) Cyt, FC, Inhib Chimeric antibody (mouse/human)
TAB-498LC Anti-Human CLDN3 Recombinant Antibody (Chimeric CDN28) Cyt, FC, Inhib Chimeric antibody (mouse/human)
TAB-499LC Anti-Human CLDN3 Recombinant Antibody (Chimeric CDN35) Cyt, FC, Inhib Chimeric antibody (mouse/human)

Mouse Antibody

CAT Product Name Application Type
TAB-486LC-S(P) Anti-Human CLDN3 Recombinant Antibody scFv Fragment (KM3936) WB, IP
TAB-487LC-S(P) Anti-Human CLDN3 Recombinant Antibody scFv Fragment (KM3937) WB, IP
TAB-488LC-S(P) Anti-Human CLDN3 Recombinant Antibody scFv Fragment (KM3938) WB, IP
TAB-489LC-S(P) Anti-Human CLDN3 Recombinant Antibody scFv Fragment (KM3939) WB, IP
TAB-490LC-S(P) Anti-Human CLDN3 Recombinant Antibody scFv Fragment (KM3933) WB, IP

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0150-LSX-S(P) Mouse Anti-CLDN3 Recombinant Antibody (clone CDN08); scFv Fragment ELISA, FC, FC Mouse scFv
HPAB-0151-LSX-S(P) Mouse Anti-CLDN3 Recombinant Antibody (clone CDN16); scFv Fragment ELISA, FC, FC Mouse scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0150-LSX-F(E) Mouse Anti-CLDN3 Recombinant Antibody (clone CDN08); Fab Fragment ELISA, FC, FC Mouse Fab
HPAB-0151-LSX-F(E) Mouse Anti-CLDN3 Recombinant Antibody (clone CDN16); Fab Fragment ELISA, FC, FC Mouse Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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