AbPlus™ Anti-CTSB Magnetic Beads (VS-0724-YC144)
CAT#: VS-0724-YC144
The AbPlus Anti-CTSB Magnetic Beads (VS-0724-YC144) is an innovative affinity resin which is bound with anti-CTSB specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CTSB protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoli, the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18156/150_G3_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/457/613_B10_3_selected.jpg
Normal Tissue
Figure 3 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows cytoplasmic positivity in glandular cells. Brunner's glands were also positive while Paneth cells were negative.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18156/41696_A_8_2_selected.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_A_9_4.jpg
Normal Tissue
Figure 5 Cerebral cortex
Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_B_9_5.jpg
Normal Tissue
Figure 6 Thyroid gland
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_B_1_5.jpg
Normal Tissue
Figure 7 Colon
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_A_7_3.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (BJ hTERT+, fHDF/TERT166)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164733-CTSB
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-CTSB specific antibody
- Target
- CTSB
- Immunogen
- Recombinant human Cathepsin B/CTSB, aa 18-339.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- CTSB (Cathepsin B) is a Protein Coding gene. Diseases associated with CTSB include Keratolytic Winter Erythema and Occlusion Of Gallbladder. Among its related pathways are Bacterial infections in CF airways and Innate Immune System. Gene Ontology (GO) annotations related to this gene include peptidase activity and cysteine-type peptidase activity. An important paralog of this gene is TINAGL1.
- Alternative Names
- Cathepsin B; APP Secretase; Cathepsin B1; EC 3.4.22.1; APPS; CPSB; Amyloid Precursor Protein Secretase; Cysteine Protease; EC 3.4.22;
- Gene ID
- 1508
- UniProt ID
- P07858
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CTSB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0334CT | Recombinant Mouse anti-Human CTSB Monoclonal antibody (DC242) | IHC-P | |
| MRO-1724-CN | Rabbit Anti-CTSB Polyclonal Antibody (MRO-1724-CN) | WB, IF | Rabbit IgG |
| MOB-284YJL | Rabbit Anti-CTSB Recombinant Antibody (clone CBC269) | ELISA | Rabbit IgG |
| VS3-WK1393 | Rabbit Anti-CTSB Recombinant Antibody (VS3-WK1393) | WB, ELISA | Rabbit IgG |
| VS3-FY426 | Recombinant Rabbit Anti-Ctsb Antibody (clone R08-7H4) | WB, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0866 | Hi-Affi™ Rabbit Anti-CTSB Recombinant Antibody (clone DS866AB) | WB, IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-015CN | Mouse Anti-CTSB Recombinant Antibody (clone 2A2) | ELISA, WB | Mouse IgG |
| NS-015CN-F(E) | Mouse Anti-CTSB Recombinant Antibody (clone 2A2); Fab Fragment | ELISA, WB | Mouse Fab |
| NS-015CN-S(P) | Mouse Anti-CTSB Recombinant Antibody (clone 2A2); scFv Fragment | ELISA, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1781 | Anti-Mouse CTSB Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC78 | Recombinant Anti-CTSB Eliminating Antibody, pH-Sensitive (2A2 var.) | Antigen-Sweeping In Vivo. | Mouse IgG |
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