AbPlus™ Anti-CTSB Magnetic Beads (VS-0724-YC144) (CAT#: VS-0724-YC144)
The AbPlus Anti-CTSB Magnetic Beads (VS-0724-YC144) is an innovative affinity resin which is bound with anti-CTSB specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CTSB protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoli, the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18156/150_G3_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoli, the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18156/150_G3_2_selected.jpg

Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/457/613_B10_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/457/613_B10_3_selected.jpg

Figure 3 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows cytoplasmic positivity in glandular cells. Brunner's glands were also positive while Paneth cells were negative.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18156/41696_A_8_2_selected.jpg
(Immunohistochemical staining of human duodenum shows cytoplasmic positivity in glandular cells. Brunner's glands were also positive while Paneth cells were negative.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18156/41696_A_8_2_selected.jpg

Figure 4 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_A_9_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_A_9_4.jpg

Figure 5 Cerebral cortex
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_B_9_5.jpg
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_B_9_5.jpg

Figure 6 Thyroid gland
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_B_1_5.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_B_1_5.jpg

Figure 7 Colon
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_A_7_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48998/167916_A_7_3.jpg

Figure 8 RNA cell line category: Cell line enhanced (BJ hTERT+, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164733-CTSB
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164733-CTSB
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-CTSB specific antibody
- Target
- CTSB
- Immunogen
- Recombinant human Cathepsin B/CTSB, aa 18-339.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- CTSB (Cathepsin B) is a Protein Coding gene. Diseases associated with CTSB include Keratolytic Winter Erythema and Occlusion Of Gallbladder. Among its related pathways are Bacterial infections in CF airways and Innate Immune System. Gene Ontology (GO) annotations related to this gene include peptidase activity and cysteine-type peptidase activity. An important paralog of this gene is TINAGL1.
- Alternative Names
- Cathepsin B; APP Secretase; Cathepsin B1; EC 3.4.22.1; APPS; CPSB; Amyloid Precursor Protein Secretase; Cysteine Protease; EC 3.4.22;
- Gene ID
- 1508
- UniProt ID
- P07858
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1862z | Mouse Anti-CTSB Recombinant Antibody (clone 41C6) | WB, ICC, IF, IHC | Mouse IgG1 |
MOB-0334CT | Recombinant Mouse anti-Human CTSB Monoclonal antibody (DC242) | IHC-P | |
MRO-1724-CN | Rabbit Anti-CTSB Polyclonal Antibody (MRO-1724-CN) | WB, IF | Rabbit IgG |
VS3-FY426 | Recombinant Rabbit Anti-Ctsb Antibody (clone R08-7H4) | WB, ICC, IF | Rabbit IgG |
VS13-YC270 | Rabbit Anti-CTSB Recombinant Antibody (VS13-YC270) | WB, ICC, IF, IHC-P | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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