Rabbit Anti-CYBB Recombinant Antibody (VS3-CJ383)
CAT#: VS3-CJ383
This product is a rabbit antibody that recognizes CYBB.
Gene Expression
Normal Tissue
Figure 1 High expression in spleen
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51227/136225_B_8_4_val_selected.jpg
Normal Tissue
Figure 2 Low expression in skeletal muscle
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51227/136225_B_3_6_val_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51227/136225_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51227/136225_A_7_3.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Not detected Intensity: Weak Quantity: <25% Location: Nuclear Leydig cells Staining: Not detected
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51227/136225_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (Daudi, NB-4, REH, RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000165168-CYBB
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Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat CYBB
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Western Blot.
Target
- Alternative Names
- Cytochrome b558 subunit beta; CGD; CGDX; NOX2; IMD34; AMCBX2; GP91-1; GP91PHOX; p91-PHOX; GP91-PHOX
- Gene ID
- 1536
- UniProt ID
- P04839
- Cellular Localization
- Cell membrane, Membrane
- Post Translation Modifications
- Glycosylated.
Phosphorylated on Ser and Thr residues.
Undergoes 'Lys-48'-linked polyubiquitination, likely by RNF145, triggering endoplasmic reticulum-associated degradation.
- Protein Refseq
- NP_000388.2
- Function
- Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "CYBB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0894 | Hi-Affi™ Rabbit Anti-CYBB Recombinant Antibody (clone DS894AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1104-CN | Rabbit Anti-CYBB Recombinant Antibody (clone CBACN-406) | WB | Rabbit IgG |
| VS1-YJ149 | Mouse Anti-CYBB Recombinant Antibody (clone 54.1) | WB | Mouse IgG1 |
| VS1-YJ150 | Mouse Anti-CYBB Recombinant Antibody (clone 54.1), HRP | WB, ICC, IF, IHC-P | Mouse IgG1 |
| VS1-YJ151 | Mouse Anti-CYBB Recombinant Antibody (clone CL5) | WB | Mouse IgG1 |
| VS1-YJ152 | Mouse Anti-CYBB Recombinant Antibody (clone NL7) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY599 | Anti-CYBB Immunohistochemistry Kit | IHC | |
| VS-0525-XY1837 | Anti-Human CYBB Immunohistochemistry Kit | IHC |
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