Mouse Anti-CYLD Recombinant Antibody (CY996)
CAT#: VS-0326-YC996
The anti-CYLD recombinant antibody (CY996) reacts with human, mouse and rat CYLD. CYLD is a deubiquitinating enzyme that specifically removes K63-linked ubiquitin chains from signaling molecules like TRAF2 and NEMO. By doing so, it acts as a powerful brake on NF-κB and JNK signaling. CYLD is a tumor suppressor; its loss leads to uncontrolled inflammatory signaling and the development of cylindromatosis (skin tumors). The anti-CYLD antibody (CY996) has been tested in Flow Cytometry (FC) and Western Blot (WB).
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human, Mouse and Rat CYLD
- Species Reactivity
- Human, Mouse, Rat
- Clone
- CY996
- Applications
- FC, WB
- Conjugate
- The unconjugated, Biotin and FITC formats are available.
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- WB (1/1000-1/2000), FC (1/25-1/50)
Target
- Alternative Names
- CYLD Lysine 63 Deubiquitinase; Ubiquitin-Specific-Processing Protease CYLD; Cylindromatosis (Turban Tumor Syndrome); Ubiquitin Specific Peptidase Like 2; Deubiquitinating Enzyme CYLD; Ubiquitin Thioesterase CYLD; CYLD1; Probable Ubiquitin Carboxyl-Terminal Hydrolase CYLD; Ubiquitin Carboxyl-Terminal Hydrolase CYLD; Ubiquitin Thiolesterase CYLD; EC 3.4.19.12; EC 3.1.2.15;
- Gene ID
- 1540
- UniProt ID
- Q9NQC7
- Long Name
- CYLD Lysine 63 Deubiquitinase
- Post Translation Modifications
- Unmodified
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "CYLD"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1168 | Mouse Anti-CYLD Recombinant Antibody (VS3-WK1168) | WB, FC | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY2683 | Mouse Anti-CYLD Recombinant Antibody (VS3-FY2683) | FC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY151 | Mouse Anti-NHP CYLD Recombinant Antibody (clone 733) | WB, IHC, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS7-HM801 | Mouse Anti-CYLD Recombinant Antibody (clone 5F7F4) | FCM | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1844 | Anti-CYLD Immunohistochemistry Kit | IHC |
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