Anti-CYP17A1 (clone W24V259) Recombinant Antibody Coupled Liposome (VS-1024-FY253)
CAT#: VS-1024-FY253
Anti-CYP17A1 antibody conjugated liposomes offer a targeted approach to deliver therapeutic agents specifically to adrenocortical carcinoma cells, potentially enhancing treatment efficacy while minimizing systemic side effects. By exploiting the overexpression of CYP17A1 in these tumors, this strategy can facilitate more precise drug delivery and improve patient outcomes through reduced toxicity and enhanced tumor response. Moreover, the use of these liposomes in research can aid in understanding the molecular mechanisms underlying adrenocortical carcinoma, potentially leading to the development of novel therapeutic strategies.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/2018_B9_3_selected.jpg
Normal Tissue
Figure 2 Low expression in rectum
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_A_5_3_val_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_A_9_3.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HMC-1, SCLC-21H)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000148795-CYP17A1
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More Infomation
Specifications
- Potential Clinical Applications
- Adrenocortical carcinoma
Product Composition
- Clone
- W24V259
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- This recombinant mouse monoclonal antibody has been developed with the specific purpose of binding to CYP17A1, an enzyme critical in steroidogenesis. By interacting with CYP17A1, this antibody facilitates research into hormonal regulation and its implications in conditions such as adrenal disease and hormone-related cancers. Its design ensures high specificity, making it a valuable asset for scientists studying the intricate pathways of steroid hormone synthesis.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- CYP17A1
- Full Name
- Cytochrome P450 Family 17 Subfamily A Member 1
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0898 | Hi-Affi™ Rabbit Anti-CYP17A1 Recombinant Antibody (clone DS898AB) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0429-CN | Rabbit Anti-CYP17A1 Recombinant Antibody (clone JB93-32) | WB, IF, IHC, FC | Rabbit IgG |
| ZG-0458F | Mouse Anti-CYP17A1 Recombinant Antibody (ZG-0458F) | WB | Mouse IgG |
| VS3-QX311 | Mouse Anti-CYP17A1 Recombinant Antibody (clone 6E1-H9-F6) | WB | Mouse IgG2b |
| VS3-FY435 | Recombinant Rabbit Anti-CYP17A1 Antibody (clone R08-2J5) | WB, IHC-F, IHC-P, ICC, IF, IP | Rabbit IgG |
| VS4-WK136 | Mouse Anti-CYP17A1 Recombinant Antibody (VS4-WK136) | ELISA, WB | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY603 | Anti-CYP17A1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1846 | Anti-Mouse CYP17A1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1845 | Anti-Human CYP17A1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC280 | CytoStream™ Rabbit Anti-CYP17A1 Recombinant Antibody (VS13-YC280) | WB, ICC, IF, IHC-P, FC | Rabbit IgG |
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