Rabbit Anti-CYP17A1 Recombinant Antibody (clone JB93-32) (CAT#: MRO-0429-CN)
This antibody is a rabbit monoclonal antibody that is capable of binding to CYP17A1.
Specific Inquiry
Custom Production
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/2018_B9_3_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/2018_B9_3_selected.jpg
Figure 2 Low expression in rectum
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_A_5_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_A_5_3_val_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_B_7_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_B_7_5.jpg
Figure 4 Colon
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_A_9_3.jpg
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_A_9_3.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_A_4_6.jpg
(Cells in seminiferous ducts Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48533/142450_A_4_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (HMC-1, SCLC-21H)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000148795-CYP17A1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000148795-CYP17A1
Specifications
- Immunogen
- Recombinant protein within human Cytochrome P450 17A1 aa 1-200
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CYP17A1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- JB93-32
- Applications
- WB, IF, IHC, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Protein A affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS, pH 7.4, 1% BSA, 40% Glycerol
- Preservative
- 0.05% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Cytochrome P450 Family 17 Subfamily A Member 1; Steroid 17-Alpha-Monooxygenase; Cytochrome P450, Subfamily XVII (Steroid 17-Alpha-Hydroxylase), Adrenal Hyperplasia; Cytochrome P450, Family 17, Subfamily A, Polypeptide 1; 17-Alpha-Hydroxyprogesterone Aldolase; Cytochrome P450 17A1; Cytochrome P450-C17; Cytochrome P450c17; CYPXVII; CYP17;
- Gene ID
- 1586
- UniProt ID
- P05093
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0898 | Hi-Affi™ Rabbit Anti-CYP17A1 Recombinant Antibody (clone DS898AB) | WB, IHC | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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