AibGenesis™ Rabbit Anti-DISC1 Recombinant Antibody (AibG-Rb-IS121)
CAT#: VS14-YC321
This AI-derived anti-DISC1 antibody (AibG-Rb-IS121) is optimized for superior molecular recognition of DISC1 across human, mouse, and rat orthologs. DISC1 is a scaffold protein essential for neurodevelopment, regulating neuronal migration, neurite outgrowth, and synapse formation. It acts as a hub for Wnt and Akt signaling and its disruption is a major risk factor for psychiatric disorders.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to intermediate filaments.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48911/1647_H1_34_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (THP-1, TIME, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000162946-DISC1
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- DISC1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- AibG-Rb-IS121
- Applications
- Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC)
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% Glycerol
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (WB): 1/500-1/2000
Immunohistochemistry (IHC): 1/50-1/200
Immunocytochemistry (ICC): 1/50-1/200
Immunofluorescence (IF): 1/50-1/200
Immunoprecipitation (IP): 1/50
Target
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "DISC1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4568 | Hi-Affi™ Rabbit Anti-DISC1 Recombinant Antibody (clone TH78DS) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY578 | Mouse Anti-DISC1 Recombinant Antibody (clone 584CT4.2.1) | WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY453 | Recombinant Rabbit Anti-DISC1 Antibody (clone R03-7F5) | WB, IHC-F, IHC-P, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1998 | Anti-DISC1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1999 | Anti-Mouse DISC1 Immunohistochemistry Kit | IHC |
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