Human Anti-DOT1L Recombinant Antibody (clone 2506W1347) (CAT#: VS-0625-FY1452)
This recombinant antibody is a human IgG1 antibody, generated using recombinant antibody (rAb) phage display, and its specificity and affinity for the DOT1L protein have been confirmed under non-denaturing conditions. While no specific applications are listed, this antibody serves as a precise tool for DOT1L research. The antibody targets an epitope spanning amino acids 1-420 of the DOT1L protein, offering broad recognition and making it highly valuable for studying native DOT1L or for custom assay development.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11875/1201_C5_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11875/1201_C5_1_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71217/1400_C9_1_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71217/1400_C9_1_selected.jpg
Figure 3 IHC staining of human testis
(Immunohistochemical staining of human testis shows moderate positivity in subset of cells in seminiferous ducts.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74977/166292_A_6_6_selected.jpg
(Immunohistochemical staining of human testis shows moderate positivity in subset of cells in seminiferous ducts.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74977/166292_A_6_6_selected.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74977/166292_B_9_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74977/166292_B_9_5.jpg
Figure 5 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74977/166292_A_7_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74977/166292_A_7_5.jpg
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104885-DOT1L
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104885-DOT1L
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- The antibody reacts with human DOT1L.
- Species Reactivity
- Human
- Clone
- 2506W1347
- Applications
- ELISA, Immunoprecipitation Mass Spectrometry
Product Property
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (over 6 months). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Optimal dilutions for assays should be determined by the user.
Target
- Alternative Names
- DOT1 Like Histone Lysine Methyltransferase; Histone H3-K79 Methyltransferase; Histone Methyltransferase DOT1L; Lysine N-Methyltransferase 4; DOT1-Like Protein; H3-K79-HMTase; KMT4; Histone-Lysine N-Methyltransferase, H3 Lysine-79 Specific
- Gene ID
- 84444
- UniProt ID
- Q8TEK3
- Long Name
- DOT1 Like Histone Lysine Methyltransferase
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "DOT1L"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Rabbit Monoclonal Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1042CT | Recombinant Mouse anti-Human DOT1L Monoclonal antibody (EML1954) | FC, IP, WB | |
| ZG-0639J | Rabbit Anti-DOT1L Recombinant Antibody (clone 3B6) | ELISA, WB | Rabbit IgG |
| VS3-FY461 | Recombinant Rabbit Anti-DOT1L Antibody (clone R01-7F6) | WB, IHC-P | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0625-FY1452. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: Neut, ELISA, FuncS
-YJ5.png)
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, Neut
Application: ELISA, Inhib, FuncS
Application: Neut, ELISA, WB, SPR, IF, EM
Application: ELISA, FC, Neut, Inhib
-2.png)
Application: WB, ELISA, FuncS
Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
