Mouse Anti-dsDNA Recombinant Antibody (clone G6-7) (CAT#: FAMAB-0151JF)
Recombinant monoclonal antibody specially binds to dsDNA. This mouse anti-dsDNA antibody G6-7 can be potentially used in the investigation of systemic lupus erythematosus (SLE).
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
FuncS
Figure 1 Distribution of anti-dsDNA IgG isotype values in SLE and controls.
Each value represents the mean ± S.E.M. of duplicate measurements from at least four independent experiments.
Villalta, D., Bizzaro, N., Bassi, N., Zen, M., Gatto, M., Ghirardello, A., ... & Doria, A. (2013). Anti-dsDNA antibody isotypes in systemic lupus erythematosus: IgA in addition to IgG anti-dsDNA help to identify glomerulonephritis and active disease. PloS one, 8(8), e71458.
FC
Figure 2 B-cell subsets at clinical relapse in patients divided according to anti-dsDNA antibody levels.
Peripheral blood B cells (gated on CD19) were analysed by flow cytometry for the expression of IgD and CD27.
Lazarus, M. N., Turner-Stokes, T., Chavele, K. M., Isenberg, D. A., & Ehrenstein, M. R. (2012). B-cell numbers and phenotype at clinical relapse following rituximab therapy differ in SLE patients according to anti-dsDNA antibody levels. Rheumatology, 51(7), 1208-1215.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- dsDNA, ssDNA
- Species Reactivity
- Human
- Clone
- G6-7
- Applications
- WB, ELISA, IF, FC, FuncS
- Related Disease
- SLE
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The dsDNA antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Flow Cytometry, Functional Assay, Immunofluorescence.
Target
- Alternative Names
- dsDNA; Double-stranded DNA
- Function
- Activating NF-κB
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-077 | Mouse Anti-dsDNA Recombinant Antibody (clone 64M-5); scFv Fragment | ELISA, WB, FuncS | Mouse scFv |
| FAMAB-0092-YC-S(P) | Mouse Anti-dsDNA Recombinant Antibody (clone 165.60); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0063WJ-S(P) | Human Anti-dsDNA Recombinant Antibody (clone KSUG); scFv Fragment | ELISA | Human scFv |
| FAMAB-0064WJ-S(P) | Human Anti-dsDNA Recombinant Antibody (clone KSUN); scFv Fragment | ELISA | Human scFv |
| FAMAB-0151JF-S(P) | Mouse Anti-dsDNA Recombinant Antibody (clone G6-7); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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