Rabbit Anti-DUSP1 Recombinant Antibody (clone R03-5D1) (CAT#: VS3-XY3339)
It is a recombinant rabbit antibody that recognizes human DUSP1 (Dual specificity phosphatase 1). It is capable of recognizing human, mouse and rat DUSP1. It has been used in a variety of applications, such as Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation, Flow cytometry, Immunocytochemistry or Immunofluorescence.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoli & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69577/1586_C7_2_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoli & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69577/1586_C7_2_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (HHSteC, hTCEpi, REH)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120129-DUSP1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120129-DUSP1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat DUSP1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R03-5D1
- Applications
- WB, IHC-P, ICC, IF, IP, FC
- Related Disease
- Intellectual Developmental Disorder, X-Linked 108; Ovarian Cancer
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
IP: 1/20
FC: 1/50-1/100
Target
- Alternative Names
- HVH1; MKP1; CL100; MKP-1; PTPN10
- Gene ID
- 1843
- UniProt ID
- P28562
- Long Name
- Dual specificity phosphatase 1
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation. (P28562-DUS1_HUMAN)
Ubiquitination at Lys280 (NX_P28562 [NX_P28562-1])
Modification sites at PhosphoSitePlus
- Protein Refseq
- NP_004408.1
- Function
- Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
MHC Tetramer Products for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3320z | Mouse Anti-DUSP1 Recombinant Antibody (clone 31A1) | WB, ELISA, ICC, IF | Mouse IgG2b, κ |
| MRO-0498-CN | Rabbit Anti-DUSP1 Recombinant Antibody (clone CBACN-202) | WB, IHC, IP, FC | Rabbit IgG |
| VS3-CJ846 | Rabbit Anti-DUSP1 Recombinant Antibody (VS3-CJ846) | WB, IHC, IP, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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