Mouse Anti-EIF4E Recombinant Antibody (VS3-CJ444)
CAT#: VS3-CJ444
This product is a mouse antibody that recognizes human, mouse, and rat EIF4E.






Specifications
- Immunogen
- Recombinant protein of human IF4E
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human, Mouse, Rat EIF4E
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.09% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:4000), Immunocytochemistry (1:25).
Target
- Alternative Names
- CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1
- Gene ID
- 1977
- UniProt ID
- P06730
- Sequence Similarities
- Belongs to the eukaryotic initiation factor 4E family.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex.
- Protein Refseq
- NP_001124150.1; NP_001124151.1; NP_001317946.1
- Function
- Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
Component of a multiprotein complex that sequesters and represses translation of proneurogenic factors during neurogenesis (By similarity).
In P-bodies, component of a complex that mediates the storage of translationally inactive mRNAs in the cytoplasm and prevents their degradation (PubMed:24335285).
May play an important role in spermatogenesis through translational regulation of stage-specific mRNAs during germ cell development (By similarity).
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Related Signaling Pathways
Related Diseases
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "EIF4E"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1128 | Hi-Affi™ Rabbit Anti-EIF4E Recombinant Antibody (clone DS1128AB) | WB, IP, IHC-P, ICC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
ZG-0648J | Rabbit Anti-EIF4E Recombinant Antibody (clone 1F3) | ELISA, WB, IHC | Rabbit IgG |
VS3-QX360 | Mouse Anti-EIF4E Recombinant Antibody (clone 8C8-C10-C12) | WB | Mouse IgG1 |
VS3-QX361 | Mouse Anti-EIF4E Recombinant Antibody (clone 163CT48.1.9) | WB, ICC | Mouse IgG1, κ |
VS3-FY489 | Recombinant Rabbit Anti-EIF4E Antibody (clone R04-4H7) | WB, IHC-P, IP | Rabbit IgG |
VS3-FY490 | Recombinant Rabbit Anti-EIF4E Antibody (clone R04-5A4) | WB, IHC-F, IHC-P, ICC, IF, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0325-XY752 | Anti-EIF4E Immunohistochemistry Kit | IHC | |
VS-0525-XY2229 | Anti-Mouse EIF4E Immunohistochemistry Kit | IHC | |
VS-0525-XY2228 | Anti-Human EIF4E Immunohistochemistry Kit | IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
VS13-YC350 | CytoStream™ Rabbit Anti-EIF4E Recombinant Antibody (VS13-YC350) | WB, IHC-P, ICC, IF, FC | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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