Mouse Anti-Staphylococcus aureus PBP2a Antibody (VS-0925-XY63)
CAT#: VS-0925-XY63
Staphylococcus aureus PBP2a antibodies (duplicate) ensure consistent results, aiding flow cytometry for surface expression and studies on PBP2a inhibition by novel compounds. Reliable for combating drug-resistant MRSA.
Specifications
- Host Animal
- Mouse
- Applications
- ICC, IF, ELISA
- Specificity
- Staphylococcus aureus PBP2a
- Target
- Staphylococcus aureus PBP2a
- Immunogen
- Native Staphylococcus aureus
- Species Reactivity
- Bacteria
- Type
- Mouse IgG2a
- Purification
- Protein A Purified
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.09% sodium azide
- Storage
- This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.
Target
- Introduction
- Staphylococcus aureus PBP2a is identical to the aforementioned Penicillin-Binding Protein 2a, the key mediator of methicillin resistance in MRSA. Its low binding affinity for beta-lactam antibiotics enables MRSA to resist the action of these commonly used drugs, making MRSA infections difficult to treat. PBP2a's function in sustaining cell wall synthesis under antibiotic pressure is essential for MRSA's survival in clinical settings, where beta-lactams are widely prescribed. Detection of PBP2a or its encoding mecA gene is a gold standard for identifying MRSA in clinical samples, ensuring appropriate antibiotic selection. Research into inhibiting PBP2a focuses on developing novel compounds that bind to its active site with high affinity, restoring susceptibility to beta-lactams or directly blocking cell wall synthesis-strategies critical for combating the global spread of drug-resistant MRSA.
- Alternative Names
- S. aureus Penicillin-Binding Protein 2a, Sa PBP2a
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Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "Staphylococcus aureus PBP2a"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0925-XY62 | Mouse Anti-Staphylococcus aureus PBP2a Antibody (VS-0925-XY62) | ICC, IF | Mouse IgG2a |
| VS-0925-XY64 | Mouse Anti-Staphylococcus aureus PBP2a Antibody (VS-0925-XY64) | WB, ICC, IF, ELISA | Mouse IgG2a |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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