Mouse Anti-Staphylococcus aureus PBP2a Antibody (VS-0925-XY64)
CAT#: VS-0925-XY64
Staphylococcus aureus PBP2a antibodies (duplicate) support similar research, aiding immunoprecipitation of PBP2a complexes and validation of MRSA knockout strains. Critical for anti-MRSA therapeutic screening.
Specifications
- Host Animal
- Mouse
- Applications
- WB, ICC, IF, ELISA
- Specificity
- Staphylococcus aureus PBP2a
- Target
- Staphylococcus aureus PBP2a
- Species Reactivity
- Bacteria
- Type
- Mouse IgG2a
- Purification
- Protein A Purified
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.09% sodium azide
- Storage
- This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.
Target
- Introduction
- Staphylococcus aureus PBP2a, as the core resistance determinant of MRSA, maintains bacterial cell wall synthesis despite exposure to beta-lactam antibiotics. This protein's unique structural features prevent beta-lactams from interfering with its peptidoglycan cross-linking activity, allowing MRSA to thrive in the presence of drugs that kill susceptible Staphylococcus aureus strains. The presence of PBP2a is a defining characteristic of MRSA, and its detection is essential for guiding clinical treatment decisions-avoiding ineffective beta-lactams and choosing alternative antibiotics (e.g., vancomycin). Given the rising prevalence of MRSA and the limited number of new antibiotics, targeting PBP2a with novel inhibitors remains a top priority in antibacterial research, aiming to overcome resistance and restore the efficacy of existing drug classes.
- Alternative Names
- S. aureus Penicillin-Binding Protein 2a, Sa PBP2a
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Downloadable Resources
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Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "Staphylococcus aureus PBP2a"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0925-XY62 | Mouse Anti-Staphylococcus aureus PBP2a Antibody (VS-0925-XY62) | ICC, IF | Mouse IgG2a |
| VS-0925-XY63 | Mouse Anti-Staphylococcus aureus PBP2a Antibody (VS-0925-XY63) | ICC, IF, ELISA | Mouse IgG2a |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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