AbPlus™ Anti-EPOR Magnetic Beads (21.3.1)
CAT#: VS-0424-XY90
The AbPlus Anti-EPOR Magnetic Beads (21.3.1) is an innovative affinity resin which is bound with anti-EPOR specific antibody (21.3.1). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of EPOR protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nuclear speckles & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77654/1825_E6_47_cr5ac349555a69b_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000187266-EPOR
Normal Tissue
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nuclear speckles & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/77654/1825_E6_47_cr5ac349555a69b_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000187266-EPOR
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-EPOR specific antibody (21.3.1)
- Target
- EPOR
- Immunogen
- A 25 amino-acid synthetic peptide (LDKWLLPRNPPSEDLPGPGGSVDIV, aa 347-371) of the mature human erythropoietin receptor coupled to KLH via a C terminal cysteine.
- Target Species
- Human
- Antibody Clone
- 21.3.1
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
- Alternative Names
- Erythropoietin Receptor; EPO-R
- Gene ID
- 2057
- UniProt ID
- P19235
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1451z | Mouse Anti-EPOR Recombinant Antibody (clone 37G2) | WB, ELISA, IF, IP | Mouse IgG3, κ |
| PABW-040 | Human Anti-EPOR Recombinant Antibody (clone ABT-007) | WB, FuncS | Human IgG |
| HPAB-0490-CN | Mouse Anti-EPOR Recombinant Antibody (clone 21.3.1) | ELISA, WB, ICC, IHC, IP | Mouse IgG |
| HPAB-0491-CN | Mouse Anti-EPOR Recombinant Antibody (clone 19.1.2) | ELISA, WB, ICC, IHC, IP | Mouse IgG |
| HPAB-0169CQ | Human Anti-EPOR Recombinant Antibody (clone ABT2-SCX-012) | Agonist, ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-007WM | Anti-Human EPOR Recombinant Antibody (AB-ABT2-XG2-012) | ELISA | Human Antibody |
| TAB-007WM-S(P) | Anti-Human EPOR Recombinant Antibody scFv Fragment (AB-ABT2-XG2-012) | ELISA | Human Antibody |
| TAB-007WM-F(E) | Anti-Human EPOR Recombinant Antibody Fab Fragment (AB-ABT2-XG2-012) | ELISA | Human Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-008WM | Anti-Human EPOR Recombinant Antibody (1E3) | ELISA, WB, FC | |
| TAB-008WM-S(P) | Anti-Human EPOR Recombinant Antibody scFv Fragment (1E3) | ELISA, WB, FC | |
| TAB-009WM-S(P) | Mouse Anti-EPOR Recombinant Antibody; scFv Fragment (TAB-009WM-S(P)) | WB, FC | Mouse scFv |
| TAB-008WM-F(E) | Anti-Human EPOR Recombinant Antibody Fab Fragment (1E3) | ELISA, WB, FC | |
| TAB-009WM-F(E) | Mouse Anti-EPOR Recombinant Antibody; Fab Fragment (TAB-009WM-F(E)) | WB, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-736CQ | Mouse Anti-EPOR Recombinant Antibody (clone CBL641) | Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1173 | Hi-Affi™ Rabbit Anti-EPOR Recombinant Antibody (clone DS1173AB) | IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0490-CN-F(E) | Mouse Anti-EPOR Recombinant Antibody (clone 21.3.1); Fab Fragment | ELISA, WB, ICC, IHC, IP | Mouse Fab |
| HPAB-0491-CN-F(E) | Mouse Anti-EPOR Recombinant Antibody (clone 19.1.2); Fab Fragment | ELISA, WB, ICC, IHC, IP | Mouse Fab |
| HPAB-0359-YJ-F(E) | Human Anti-EPOR Recombinant Antibody; Fab Fragment (HPAB-0359-YJ-F(E)) | ELISA, FC, Activ, FuncS | Human Fab |
| HPAB-1306WJ-F(E) | Mouse Anti-EPOR Recombinant Antibody (clone 3G9); Fab Fragment | ELISA, WB, Agonist | Mouse Fab |
| HPAB-1307WJ-F(E) | Human Anti-EPOR Recombinant Antibody (clone 3G9HZLC); Fab Fragment | ELISA, WB, Agonist | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0169CQ-S(P) | Human Anti-EPOR Recombinant Antibody (clone ABT2-SCX-012); scFv Fragment | Agonist, ELISA | Human scFv |
| HPAB-0359-YJ-S(P) | Human Anti-EPOR Recombinant Antibody; scFv Fragment (HPAB-0359-YJ-S(P)) | ELISA, FC, Activ, FuncS | Human scFv |
| HPAB-0360-YJ-S(P) | Human Anti-EPOR Recombinant Antibody; scFv Fragment (HPAB-0360-YJ-S(P)) | ELISA, FC, Activ, FuncS | Human scFv |
| HPAB-1306WJ-S(P) | Mouse Anti-EPOR Recombinant Antibody (clone 3G9); scFv Fragment | ELISA, WB, Agonist | Mouse scFv |
| HPAB-1307WJ-S(P) | Human Anti-EPOR Recombinant Antibody (clone 3G9HZLC); scFv Fragment | ELISA, WB, Agonist | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY17 | Human Anti-EpoR (clone 10) scFv-Fc Chimera | ELISA, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC620 | Recombinant Anti-EPOR Vesicular Antibody, EV Displayed (VS-0425-YC620) | Agonist, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC70 | Recombinant Anti-EPOR (AA 347-371 x AA 382-402) Biparatopic Antibody, Tandem scFv (Clone 21.3.1 x Clone 19.1.2) | ELISA, ICC, IHC, IP, WB | Tandem scFv |
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