Recombinant Anti-EPOR Vesicular Antibody, EV Displayed (VS-0425-YC620)
CAT#: VS-0425-YC620
The Recombinant Anti-EPOR Vesicular Antibody, EV Displayed (VS-0425-YC620) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to EPOR-expressed cells or tissues. EPOR is an erythropoietin receptor affecting erythroid cell survival, with mutation-related role in erythroleukemia and familial erythrocytosis.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nuclear speckles & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77654/1825_E6_47_cr5ac349555a69b_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000187266-EPOR
Normal Tissue
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nuclear speckles & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/77654/1825_E6_47_cr5ac349555a69b_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000187266-EPOR
❮
❯
Recombinant Antibody
- Application
- Agonist, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- EPOR
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Erythropoietin receptor
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane, Nuclear speckles
- Introduction
- This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
- Gene ID
- 2057
- UniProt ID
- P19235
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1451z | Mouse Anti-EPOR Recombinant Antibody (clone 37G2) | WB, ELISA, IF, IP | Mouse IgG3, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABW-040 | Human Anti-EPOR Recombinant Antibody (clone ABT-007) | WB, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-040 | Human Anti-EPOR Recombinant Antibody (clone ABT-007); Fab Fragment | WB, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBW-040 | Human Anti-EPOR Recombinant Antibody (clone ABT-007); scFv Fragment | WB, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-007WM | Anti-Human EPOR Recombinant Antibody (AB-ABT2-XG2-012) | ELISA | Human Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-008WM | Anti-Human EPOR Recombinant Antibody (1E3) | ELISA, WB, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-009WM | Mouse Anti-EPOR Recombinant Antibody (TAB-009WM) | WB, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-007WM-S(P) | Anti-Human EPOR Recombinant Antibody scFv Fragment (AB-ABT2-XG2-012) | ELISA | Human Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-008WM-S(P) | Anti-Human EPOR Recombinant Antibody scFv Fragment (1E3) | ELISA, WB, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-009WM-S(P) | Mouse Anti-EPOR Recombinant Antibody; scFv Fragment (TAB-009WM-S(P)) | WB, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-007WM-F(E) | Anti-Human EPOR Recombinant Antibody Fab Fragment (AB-ABT2-XG2-012) | ELISA | Human Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-008WM-F(E) | Anti-Human EPOR Recombinant Antibody Fab Fragment (1E3) | ELISA, WB, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0682CT | Recombinant Mouse anti-Human EPOR Monoclonal antibody (EML077) | WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-736CQ | Mouse Anti-EPOR Recombinant Antibody (clone CBL641) | Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1173 | Hi-Affi™ Rabbit Anti-EPOR Recombinant Antibody (clone DS1173AB) | IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0490-CN | Mouse Anti-EPOR Recombinant Antibody (clone 21.3.1) | ELISA, WB, ICC, IHC, IP | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0491-CN | Mouse Anti-EPOR Recombinant Antibody (clone 19.1.2) | ELISA, WB, ICC, IHC, IP | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0490-CN-S(P) | Mouse Anti-EPOR Recombinant Antibody (clone 21.3.1); scFv Fragment | ELISA, WB, ICC, IHC, IP | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0491-CN-S(P) | Mouse Anti-EPOR Recombinant Antibody (clone 19.1.2); scFv Fragment | ELISA, WB, ICC, IHC, IP | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0490-CN-F(E) | Mouse Anti-EPOR Recombinant Antibody (clone 21.3.1); Fab Fragment | ELISA, WB, ICC, IHC, IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0491-CN-F(E) | Mouse Anti-EPOR Recombinant Antibody (clone 19.1.2); Fab Fragment | ELISA, WB, ICC, IHC, IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0169CQ-F(E) | Human Anti-EPOR Recombinant Antibody (clone ABT2-SCX-012); Fab Fragment | Agonist, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0169CQ-S(P) | Human Anti-EPOR Recombinant Antibody (clone ABT2-SCX-012); scFv Fragment | Agonist, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0359-YJ-S(P) | Human Anti-EPOR Recombinant Antibody; scFv Fragment (HPAB-0359-YJ-S(P)) | ELISA, FC, Activ, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0359-YJ-F(E) | Human Anti-EPOR Recombinant Antibody; Fab Fragment (HPAB-0359-YJ-F(E)) | ELISA, FC, Activ, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY90 | AbPlus™ Anti-EPOR Magnetic Beads (21.3.1) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY17 | Human Anti-EpoR (clone 10) scFv-Fc Chimera | ELISA, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC70 | Recombinant Anti-EPOR (AA 347-371 x AA 382-402) Biparatopic Antibody, Tandem scFv (Clone 21.3.1 x Clone 19.1.2) | ELISA, ICC, IHC, IP, WB | Tandem scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1025-YC122 | Anti-EPOR Antibody Prodrug, Protease Activated (clone 21.3.1) | ISZ, Cyt, FuncS |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0126-XL1992 | Rabbit Anti-EpoR (phospho Y426) Antibody | Phospho Antibodies for Cell Signaling Research |
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