AbPlus™ Anti-ESR1 Magnetic Beads (33)
CAT#: VS-0424-XY93
The AbPlus Anti-ESR1 Magnetic Beads (33) is an innovative affinity resin which is bound with anti-ESR1 specific antibody (33). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of ESR1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1134_D1_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1423_D4_1_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1_G2_1_blue_red_green.jpg
Normal Tissue
Figure 4 Endometrium
Cells in endometrial stroma
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37/288_B_3_3.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (MCF7, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091831-ESR1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-ESR1 specific antibody (33)
- Target
- ESR1
- Immunogen
- Synthetic peptide corresponding to the residues 247-261 (EVGMMKGGIRKDRRG) of the ER alpha DNA binding domain
- Target Species
- Human, Mouse, Rat, Fish, Primate, Sheep, Bovine, Avian
- Antibody Clone
- 33
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- ESR1 estrogen receptor 1 This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. ER; ESR; Era; ESRA; ESTRR; NR3A1
- Alternative Names
- ESR1; estrogen receptor 1; ER; ESR; Era; ESRA; ESTRR; NR3A1
- Gene ID
- 2099
- UniProt ID
- P03372
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ESR1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-898-VHH | Recombinant Anti-Human ESR1 VHH Single Domain Antibody | FA, FC, ICC, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0197MZ | Chicken Anti-ESR1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-750CQ | Mouse Anti-ESR1 Recombinant Antibody (clone 33) | Block, FC, GS, ELISA, ICC, IF, IHC, IHC-Fr, IHC-P, IP, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-751CQ | Mouse Anti-ESR1 Recombinant Antibody (clone TE111.5D11) | FC, IP, WB, Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1201 | Hi-Affi™ Rabbit Anti-ESR1 Recombinant Antibody (clone DS1201AB) | IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1849-CN | Rabbit Anti-ESR1 Polyclonal Antibody (MRO-1849-CN) | WB, IF, FC | Rabbit IgG |
| VS3-CJ318 | Mouse Anti-ESR1 Recombinant Antibody (VS3-CJ318) | IHC | Mouse IgG2b |
| VS3-CJ319 | Rabbit Anti-ESR1 Recombinant Antibody (VS3-CJ319) | WB, ICC, IF, IHC | Rabbit IgG |
| VS3-XY651 | Mouse Anti-ESR1 Recombinant Antibody (clone 2B7) | ELISA, WB, IHC | Mouse IgG1 |
| VS11-QX63 | Mouse Anti-ESR1 Recombinant Antibody (clone 4E11) | ELISA | Mouse IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY193 | Mouse Anti-NHP ESR1 Recombinant Antibody (clone 33) | WB, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2367 | Anti-ESR1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2368 | Anti-Mouse ESR1 Immunohistochemistry Kit | IHC |
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