AbPlus™ Anti-FADD Magnetic Beads (VS-0724-YC514)
CAT#: VS-0724-YC514
The AbPlus Anti-FADD Magnetic Beads (VS-0724-YC514) is an innovative affinity resin which is bound with anti-FADD specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of FADD protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, cytosol & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1464/69_A10_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10209/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human gallbladder
Immunohistochemical staining of human gallbladder shows cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1464/34820_A_4_4_selected.jpg
Normal Tissue
Figure 4 IHC staining of human stomach
Immunohistochemical staining of human stomach shows moderate cytoplasmic and nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10209/ihc_selected.jpg
Normal Tissue
Figure 5 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1464/34820_B_7_5.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (A-431)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168040-FADD
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-FADD specific antibody
- Target
- FADD
- Immunogen
- Recombinant human FADD fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]
- Alternative Names
- Fas Associated Via Death Domain; Fas-Associating Death Domain-Containing Protein; Growth-Inhibiting Gene 3 Protein; Fas-Associating Protein With Death Domain; Fas (TNFRSF6)-Associated Via Death Domain; Mediator Of Receptor-Induced Toxicity;
- Gene ID
- 8772
- UniProt ID
- Q13158
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Related Diseases
Colorectal Cancer
Amyotrophic Lateral Sclerosis
Maturity Onset Diabetes of the Young
Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "FADD"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1238 | Hi-Affi™ Rabbit Anti-FADD Recombinant Antibody (clone DS1238AB) | ICC, IHC-P, IP, WB | Rabbit IgG |
| MOR-0042-FY | Rabbit Anti-FADD Recombinant Antibody (clone AFY0013) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0326J | Mouse Anti-FADD Recombinant Antibody (ZG-0326J) | WB | Mouse IgG |
| ZG-0327J | Mouse Anti-FADD Recombinant Antibody (ZG-0327J) | WB | Mouse IgG |
| ZG-0328J | Mouse Anti-FADD Recombinant Antibody (ZG-0328J) | WB | Mouse IgG |
| VS7-HM927 | Mouse Anti-FADD Recombinant Antibody (clone 5A6A2) | FCM | Mouse IgG1 |
| VS13-YC377 | Rabbit Anti-Fadd Recombinant Antibody (VS13-YC377) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY96 | AbPlus™ Anti-FADD Magnetic Beads (5A3-C7-G9) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY806 | Anti-FADD Immunohistochemistry Kit | IHC | |
| VS-0525-XY2427 | Anti-Human FADD Immunohistochemistry Kit | IHC |
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