Human Anti-FCGR2A Antibody (MDE-8), CHO Stable Cell Pool
CAT#: VS-1025-QX114
This CHO Stable Cell Pool represents a genetically engineered Chinese Hamster Ovary (CHO) cell population specifically designed for the robust and consistent expression of recombinant MDE-8. MDE-8 is a Human monoclonal antibody that targets FCGR2A. This cell pool was generated through the stable integration of genes encoding the heavy and light chains of MDE-8 into the CHO genome, followed by selection and enrichment for high-expressing cells. This cell pool provides rapid production of research-grade antibodies for non-GLP preclinical studies.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line THP-1
Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10776/1926_F1_3_selected.jpg
Subcellular Location
Figure 2 IHC staining of human placenta
Immunohistochemical staining of human placenta shows strong positivity in endothelial cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14730/ihc_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10776/1847_F1_2_blue_red_green.jpg
Normal Tissue
Figure 4 Bone marrow
Hematopoietic cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10718/26353_B_4_4.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HEL, HMC-1, K-562, NB-4, THP-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000143226-FCGR2A
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Specifications
- Host Cell
- CHO
- Product Type
- Stable Cell Pool
- Cell Viability
- >90%
- Mycoplasma Detection
- Negative
- Bacteria Detection
- Negative
- Growth Properties
- Suspension
- Culture Medium
- VersaCHO™ Medium (VS-1025-QX582)
- Complete Growth Medium
- VersaCHO™ Medium (VS-1025-QX582), VersaCHO™ Feed Medium (VS-1025-QX583), VersaCHO™ Feed Supplement (VS-1025-QX584)
- Freeze Medium
- 90% VersaCHO™ Medium, 10% DMSO
- Growth Conditions
- 37°C, 5% CO₂
- Size
- Each vial contains at least 1×10^6 cells in 1 mL
- Shipping
- Dry ice
- Storage
- Store in liquid nitrogen immediately upon receipt. Avoid multiple freeze/thaw cycles. Utilize cells within one year of the delivery date.
Antibody Overview
- Host Species
- Human
- Antibody Type
- Human Fab
- Clone
- MDE-8
- Target
- FCGR2A
- Species Reactivity
- Human
Target
- Alternative Names
- CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1; low affinity immunoglobulin gamma Fc region receptor II-a; Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc gamma receptor RIIa3; Immunoglobulin G Fc receptor II; fc-gamma-RIIa; fcRII-a; igG Fc receptor II-a
- Gene ID
- 2212
- UniProt ID
- P12318
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Datasheet
MSDS
COA
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