CytoStream™ Rabbit Anti-FKBP4 Recombinant Antibody (VS13-YC402)
CAT#: VS13-YC402
The CytoStream™ Rabbit Anti-FKBP4 Recombinant Antibody is specific for human and mouse FKBP4. FKBP4, also in the immunophilin family, lacks immunosuppressant activity, instead interacting with regulatory factors affecting B and T lymphocyte signaling, playing roles in intracellular trafficking and gene therapy enhancements. The anti-FKBP4 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6148/35_G6_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62857/1230_E5_2_selected.jpg
Normal Tissue
Figure 3 Vagina
Squamous epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62857/168946_B_1_2.jpg
Normal Tissue
Figure 4 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62857/168946_A_8_8.jpg
Normal Tissue
Figure 5 Cerebral cortex
Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62857/168946_B_8_5.jpg
Normal Tissue
Figure 6 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62857/168946_A_7_3.jpg
Normal Tissue
Figure 7 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62857/168946_A_9_5.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000004478-FKBP4
❮
❯
Specifications
- Immunogen
- Recombinant human FKBP52, aa 1-132.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse FKBP4
- Species Reactivity
- Human, Mouse
- Applications
- WB, ICC, IF, IHC-P, FC
- Conjugate
- NONE
- Related Disease
- Paralytic Lagophthalmos and Facial Nerve Disease
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/1000-1/2000
Immunocytochemistry (ICC): 1/50-1/200
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- FK506 Binding Protein 4; FK506 Binding Protein 4, 59kDa; EC 5.2.1.8; Rotamase; FKBP51; FKBP52; FKBP59; HBI; Peptidyl-Prolyl Cis-Trans Isomerase FKBP4; T-Cell FK506-Binding Protein, 59kD; Peptidylprolyl Cis-Trans Isomerase; FK506-Binding Protein 4 (59kD); 51 KDa FK506-Binding Protein; 52 KDa FK506-Binding Protein;
- Gene ID
- 2288
- UniProt ID
- Q02790
- Long Name
- FK506 Binding Protein 4
- Cellular Localization
- Cytoplasm; Cytoskeleton; Microtubule; Mitochondrion; Nucleus
- Protein Refseq
- XP_047284495.1; NP_002005.1
- Function
- May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS13-YC402. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "FKBP4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0584CT | Recombinant Mouse anti-Human FKBP4 Monoclonal antibody (EML311) | ICC, IF, IHC-P, WB | |
| MRO-0594-CN | Rabbit Anti-FKBP4 Recombinant Antibody (clone JG96-30) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-WK337 | Rabbit Anti-FKBP4 Recombinant Antibody (clone JB95-39) | WB, ELISA | Rabbit IgG |
| VS3-FY2004 | Rabbit Anti-FKBP4 Recombinant Antibody (clone R08-4F8) | WB, IHC-P | Rabbit IgG |
| VS3-FY2709 | Rabbit Anti-FKBP4 Recombinant Antibody (VS3-FY2709) | WB, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-843CQ | Mouse Anti-FKBP4 Recombinant Antibody (clone KN382/EC1) | IHC-Fr, WB, IP, RIA, ICC, Block, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1310 | Hi-Affi™ Rabbit Anti-FKBP4 Recombinant Antibody (clone DS1310AB) | WB, IHC, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY844 | Anti-FKBP4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2563 | Anti-Mouse FKBP4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2562 | Anti-Human FKBP4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2564 | Anti-Rat FKBP4 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
-2.png)
Application: ELISA, FC, WB, Block
Application: Block, IP, IF, FC
Application: Inhib, FC, WB
Application: ELISA, Inhib, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
