Human Anti-FZD7 Recombinant Antibody scFv Fragment (PABJ-0125-S(P)) (CAT#: PABJ-0125-S(P))
This product is a Human antibody scFv fragment that recognizes Human FZD7. This antibody bound to FZD1, -2, -5, -7, and -8, but not FZD4. It showed cross-reactivity to mouse FZD4 and FZD5. It functionally inhibited Wnt3a-induced β-catenin stabilization in 32D cells expressing each of their respective FZD-binding partners.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59979/1801_H6_7_cr59ca18578e0d0_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59979/1801_H6_7_cr59ca18578e0d0_selected.jpg
Figure 2 IHC staining of human fallopian tube
(Immunohistochemical staining of human fallopian tube shows strong cytoplasmic positivity with a granular pattern in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_A_9_7_selected.jpg
(Immunohistochemical staining of human fallopian tube shows strong cytoplasmic positivity with a granular pattern in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_A_9_7_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_B_9_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_B_9_5.jpg
Figure 4 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_A_7_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_A_7_3.jpg
Figure 5 Liver
(Cholangiocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_A_9_4.jpg
(Cholangiocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_A_9_4.jpg
Figure 6 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_A_8_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_A_8_5.jpg
Figure 7 Testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Leydig cells Staining: Low Intensity: Weak Quantity:>75% Pachytene spermatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Preleptotene spermatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Low Intensity: Weak Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_A_6_6.jpg
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Leydig cells Staining: Low Intensity: Weak Quantity:>75% Pachytene spermatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Preleptotene spermatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Low Intensity: Weak Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69165/157344_A_6_6.jpg
Figure 8 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, CAPAN-2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000155760-FZD7
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000155760-FZD7
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human FZD7
- Species Reactivity
- Human
- Applications
- ELISA, Inhib
Product Property
- Purification
- Purified
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Inhibition.
Target
- Alternative Names
- FzE3; frizzled-7; Frizzled, drosophila, homolog of, 7; frizzled 7, seven transmembrane spanning receptor; frizzled family receptor 7; frizzled homolog 7; fz-7; hFz7; Frizzled class receptor 7; cysteine-rich domain; CRD
- Gene ID
- 8324
- UniProt ID
- O75084
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-033CQ | Mouse Anti-FZD7 Recombinant Antibody (TAB-033CQ) | ELISA, FC, WB | Mouse IgG |
| TAB-033CQ-S(P) | Mouse Anti-FZD7 Recombinant Antibody; scFv Fragment (TAB-033CQ-S(P)) | ELISA, FC, WB | Mouse scFv |
| TAB-033CQ-F(E) | Mouse Anti-FZD7 Recombinant Antibody; Fab Fragment (TAB-033CQ-F(E)) | ELISA, FC, WB | Mouse Fab |
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