Mouse Anti-GAST Recombinant Antibody (VS3-CJ262)
CAT#: VS3-CJ262
This product is a mouse antibody that recognizes GAST.
Gene Expression
Normal Tissue
Figure 1 Stomach
Glandular cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38/266_A_3_1.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184502-GAST
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Specifications
- Immunogen
- KLH-conjugated synthetic peptide encompassing a sequence within human Gastrin
- Host Species
- Mouse
- Type
- Mouse IgG3
- Specificity
- Human GAST
- Species Reactivity
- Human
- Applications
- IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Immunogen affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.2% BSA, PBS.
- Preservative
- 0.01% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Immunohistochemistry (1:100-1:300).
Target
- Alternative Names
- GAS; Gastrin
- Gene ID
- 2520
- UniProt ID
- P01350
- Sequence Similarities
- Belongs to the gastrin/cholecystokinin family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.
Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific.
- Protein Refseq
- NP_000796.1
- Function
- Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "GAST"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1241z | Mouse Anti-GAST Recombinant Antibody (clone 30D9) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| ZG-0069C | Mouse Anti-GAST Recombinant Antibody (clone ABT-GAST) | IHC-P, IF | Mouse IgG |
| ZG-0070C | Mouse Anti-GAST Recombinant Antibody (clone PT0139) | IHC-P, IF | Mouse IgG |
| VS3-QX462 | Mouse Anti-GAST Recombinant Antibody (clone 486CT4.8.13.6) | WB | Mouse IgG1 |
| VS3-FY578 | Recombinant Mouse Anti-GAST Antibody (clone 10E2-3D1-6D3) | IHC-P | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-047CQ | Mouse Anti-GAST Recombinant Antibody (TAB-047CQ) | ELISA, IHC, IF | Mouse IgG1 |
| TAB-048CQ | Mouse Anti-GAST Recombinant Antibody (TAB-048CQ) | ELISA, IHC, IF | Mouse IgG1 |
| TAB-047CQ-S(P) | Mouse Anti-GAST Recombinant Antibody; scFv Fragment (TAB-047CQ-S(P)) | ELISA, IHC, IF | Mouse scFv |
| TAB-048CQ-S(P) | Mouse Anti-GAST Recombinant Antibody; scFv Fragment (TAB-048CQ-S(P)) | ELISA, IHC, IF | Mouse scFv |
| TAB-049CQ-S(P) | Mouse Anti-GAST Recombinant Antibody; scFv Fragment (TAB-049CQ-S(P)) | ELISA, IHC, IF | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY900 | Anti-GAST Immunohistochemistry Kit | IHC | |
| VS-0525-XY2739 | Anti-Human GAST Immunohistochemistry Kit | IHC |
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