Rabbit Anti-GCSAM Recombinant Antibody (VS13-YC440) (CAT#: VS13-YC440)
The Rabbit Anti-GCSAM Recombinant Antibody is specific for human GCSAM. GCSAM is an immune-based signal transduction protein induced by interleukin-4, impacting germinal cell lymphomas through domains like ITAM, affecting lymphocyte pathways. The anti-GCSAM antibody can be used for Immunohistochemistry (1/100-1/200).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Specifications
- Immunogen
- Recombinant human GCET2.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human GCSAM
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
- Related Disease
- Lymphoma and Diffuse Large B-Cell Lymphoma
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- Germinal Center Associated Signaling And Motility; Germinal Center B-Cell-Expressed Transcript 2 Protein; Germinal Center-Associated Lymphoma Protein; Human Germinal Center-Associated Lymphoma; Germinal Center Expressed Transcript 2; GCET2;
- Gene ID
- 257144
- UniProt ID
- Q8N6F7
- Long Name
- Germinal Center Associated Signaling And Motility
- Cellular Localization
- Cell membrane; Cytoplasm; Membrane
- Protein Refseq
- XP_011510929.1; XP_011510931.1; XP_011510932.1; XP_024309205.1; XP_024309206.1
- Function
- Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY1725 | Rabbit Anti-GCSAM Recombinant Antibody (clone R05-4H2) | WB, IHC-Fr, IHC-P, IF | Rabbit IgG |
| VS3-XY3367 | Rabbit Anti-GCSAM Recombinant Antibody (clone R03-7X6) | IHC-P, ICC, IF, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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