Rabbit Anti-GCSAM Recombinant Antibody (VS13-YC440) (CAT#: VS13-YC440)

• Immunogen
• Recombinant human GCET2.

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human GCSAM

• Species Reactivity
• Human

• Applications
• IHC-P

• Conjugate
• NONE

• Related Disease
• Lymphoma and Diffuse Large B-Cell Lymphoma

• Clonality
• Monoclonal

• Purification
• Affinity Chromatography purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.

• Preservative
• 0.02% Sodium azide

• Storage
• Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Shipping with ice pack.

• Application Notes
• Immunohistochemistry (IHC): 1/100-1/200

• Alternative Names
• Germinal Center Associated Signaling And Motility; Germinal Center B-Cell-Expressed Transcript 2 Protein; Germinal Center-Associated Lymphoma Protein; Human Germinal Center-Associated Lymphoma; Germinal Center Expressed Transcript 2; GCET2;

• Gene ID
• 257144

• UniProt ID
• Q8N6F7

• Long Name
• Germinal Center Associated Signaling And Motility

• Cellular Localization
• Cell membrane; Cytoplasm; Membrane

• Protein Refseq
• XP_011510929.1; XP_011510931.1; XP_011510932.1; XP_024309205.1; XP_024309206.1

• Function
• Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-061CQ
• Sheep Anti-Rabbit IgG (H&L) Antibody

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

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