Rabbit Anti-GCSAM Recombinant Antibody (clone R05-4H2) (CAT#: VS3-FY1725)
This is a IHC function antibody that was produced by immunizing with recombinant human GCSAM protein. This recombinant monoclonal antibody exhibits high affinity for human GCSAM. The antibody was purified by affinity chromatography. The R05-4H2 is recommended for dilution of target protein by western blot (dilution 1/500-1/1000), immunohistochemistry (dilution 1/50-1/100), immunofluorescence (dilution 1/50-1/200).
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Specifications
- Immunogen
- Recombinant human GCET2 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human GCSAM
- Species Reactivity
- Human
- Clone
- R05-4H2
- Applications
- Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunofluorescence
- MW
- The calculated weight of the target protein is approximately 21 kDa, while the observed molecular weight stands at 21 kDa.
- Related Disease
- Lymphoma and Diffuse Large B-Cell Lymphoma
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunofluorescence: 1/50-1/200
Target
- Alternative Names
- Germinal Center Associated Signaling And Motility; Germinal Center B-Cell-Expressed Transcript 2 Protein; Germinal Center-Associated Lymphoma Protein; Human Germinal Center-Associated Lymphoma; Germinal Center Expressed Transcript 2; GCET2
- Gene ID
- 257144
- UniProt ID
- Q8N6F7
- Cellular Localization
- Cell membrane, Cytoplasm, Membrane
- Post Translation Modifications
- Phosphorylation on tyrosine residues can be induced by IL6. Phosphorylation is mediated by LYN.
- Protein Refseq
- XP_011510929.1; XP_011510931.1; XP_011510932.1; XP_024309205.1; XP_024309206.1
- Function
- Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY3367 | Rabbit Anti-GCSAM Recombinant Antibody (clone R03-7X6) | IHC-P, ICC, IF, FC | Rabbit IgG |
| VS13-YC440 | Rabbit Anti-GCSAM Recombinant Antibody (VS13-YC440) | IHC-P | Rabbit IgG |
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