Human Anti-GM2 Recombinant Antibody Hexamer (VS-0924-YC130), CDC Enhanced (CAT#: VS-0924-YC130)
The product is a human anti-GM2 antibody hexamer with enhanced complement-dependent cytotoxicity (CDC) activity. This hexameric IgG1 targets human GM2 and contains hexamerization-enhancing mutations that promote hexamer formation. These mutations facilitate optimal C1q binding, thereby enhancing CDC.
Specific Inquiry
Specifications
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Antibody hexamer
- Specificity
- Human GM2
- Species Reactivity
- Human
- Molecule Class
- ~ 900 kDa
- Applications
- ELISA, IF, ADCC, CDC, Cyt
- Conjugate
- None
- Related Disease
- Tumor
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% determined as SDS-PAGE and SEC-HPLC
- Aggregation
- <5%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Ganglioside GM2; GM2
- Long Name
- GM2 ganglioside
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Hexamer Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-406 | Recombinant Anti-GM2 Antibody | ELISA, WB, IF, FuncS | IgG |
| MHH-406 | Recombinant Human Anti-GM2 Antibody | WB, Neut, FuncS | IgG |
| HPAB-S0039-YC | Human Anti-GM2 Recombinant Antibody (clone KM8966) | ELISA, ADCC | Human IgG |
| FAMAB-1396CQ | Mouse Anti-GM2 Recombinant Antibody (clone E1) | ELISA, IHC | Mouse IgG1 |
| HPAB-A1367-YJ | Human Anti-GM2 Recombinant Antibody (clone KM966) | ELISA, IF, ADCC, CDC, Cyt, FuncS | Chimeric (mouse/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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