Rabbit Anti-GRIA1 Recombinant Antibody (VS13-YC466) (CAT#: VS13-YC466)
The Rabbit Anti-GRIA1 Recombinant Antibody is specific for human, mouse and rat GRIA1. GRIA1, part of AMPA receptor family, facilitates excitatory neurotransmission, influencing synaptic activity through ligand-gated ion channels and splicing variations. The anti-GRIA1 antibody can be used for Western blot (1/500-1/2000), Immunohistochemistry-paraffin (1/50-1/200).
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Hippocampal formation
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/ihc_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_B_7_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_B_7_5.jpg
Figure 3 Hippocampus
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_B_7_6.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_B_7_6.jpg
Figure 4 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_A_8_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_A_8_5.jpg
Figure 5 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_A_8_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (AF22, ASC diff, BJ, BJ hTERT+, LHCN-M2, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000155511-GRIA1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000155511-GRIA1
Specifications
- Immunogen
- Recombinant human glutamate receptor 1, aa 857-906.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat GRIA1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, IP
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Target
- Alternative Names
- Glutamate Ionotropic Receptor AMPA Type Subunit 1; Glutamate Receptor, Ionotropic, AMPA 1; AMPA-Selective Glutamate Receptor 1; GluR-K1; GluR-1; GluR-A; GLUR1; GLUH1;
- Gene ID
- 2890
- UniProt ID
- P42261
- Long Name
- Glutamate Ionotropic Receptor AMPA Type Subunit 1
- Sequence Similarities
- Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA1 subfamily.
- Cellular Localization
- Cell membrane; Cell projection; Endoplasmic reticulum; Endosome; Postsynaptic cell membrane; Synapse
- Protein Refseq
- NP_000818.2; NP_001107655.1; NP_001244948.1
- Function
- Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2122z | Mouse Anti-GRIA1 Recombinant Antibody (clone 37D7) | WB, ICC, IF, IHC | Mouse IgG1 |
| MRO-0674-CN | Rabbit Anti-GRIA1 Recombinant Antibody (clone CBACN-245) | WB, IHC, IP | Rabbit IgG |
| VS3-CJ949 | Rabbit Anti-GRIA1 Recombinant Antibody (VS3-CJ949) | WB, IHC, IP | Rabbit IgG |
| VS3-CJ950 | Rabbit Anti-GRIA1 (phospho S845) Recombinant Antibody (VS3-CJ950) | WB, FC | Rabbit IgG |
| VS3-FY614 | Recombinant Rabbit Anti-GRIA1 (phospho Ser845) Antibody (clone R03-7G4) | WB | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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