Rabbit Anti-GRIA1 Recombinant Antibody (VS13-YC466) (CAT#: VS13-YC466)
The Rabbit Anti-GRIA1 Recombinant Antibody is specific for human, mouse and rat GRIA1. GRIA1, part of AMPA receptor family, facilitates excitatory neurotransmission, influencing synaptic activity through ligand-gated ion channels and splicing variations. The anti-GRIA1 antibody can be used for Western blot (1/500-1/2000), Immunohistochemistry-paraffin (1/50-1/200).
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/ihc_selected.jpg

(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_B_7_5.jpg

(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_B_7_6.jpg

(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_A_8_5.jpg

(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_A_8_8.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000155511-GRIA1
Specifications
- Immunogen
- Recombinant human glutamate receptor 1, aa 857-906.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat GRIA1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, IP
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Target
- Alternative Names
- Glutamate Ionotropic Receptor AMPA Type Subunit 1; Glutamate Receptor, Ionotropic, AMPA 1; AMPA-Selective Glutamate Receptor 1; GluR-K1; GluR-1; GluR-A; GLUR1; GLUH1;
- Gene ID
- 2890
- UniProt ID
- P42261
- Long Name
- Glutamate Ionotropic Receptor AMPA Type Subunit 1
- Sequence Similarities
- Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA1 subfamily.
- Cellular Localization
- Cell membrane; Cell projection; Endoplasmic reticulum; Endosome; Postsynaptic cell membrane; Synapse
- Protein Refseq
- NP_000818.2; NP_001107655.1; NP_001244948.1
- Function
- Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "GRIA1"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1504 | Rabbit Anti-GRIA1 Recombinant Antibody (clone DS1504AB) | IHC-P, IP, WB | Rabbit IgG |
MOR-0035-FY | Rabbit Anti-GRIA1 Recombinant Antibody (clone AFY0006) | IHC-P, WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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