Rabbit Anti-GRIA1 Recombinant Antibody (VS13-YC466)
CAT#: VS13-YC466
The Rabbit Anti-GRIA1 Recombinant Antibody is specific for human, mouse and rat GRIA1. GRIA1, part of AMPA receptor family, facilitates excitatory neurotransmission, influencing synaptic activity through ligand-gated ion channels and splicing variations. The anti-GRIA1 antibody can be used for Western blot (1/500-1/2000), Immunohistochemistry-paraffin (1/50-1/200).
Gene Expression
Normal Tissue
Figure 1 Hippocampal formation
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_B_7_5.jpg
Normal Tissue
Figure 3 Hippocampus
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_B_7_6.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_A_8_5.jpg
Normal Tissue
Figure 5 Lymph node
Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35202/135520_A_8_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (AF22, ASC diff, BJ, BJ hTERT+, LHCN-M2, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000155511-GRIA1
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Specifications
- Immunogen
- Recombinant human glutamate receptor 1, aa 857-906.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat GRIA1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, IP
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Target
- Alternative Names
- Glutamate Ionotropic Receptor AMPA Type Subunit 1; Glutamate Receptor, Ionotropic, AMPA 1; AMPA-Selective Glutamate Receptor 1; GluR-K1; GluR-1; GluR-A; GLUR1; GLUH1;
- Gene ID
- 2890
- UniProt ID
- P42261
- Long Name
- Glutamate Ionotropic Receptor AMPA Type Subunit 1
- Sequence Similarities
- Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA1 subfamily.
- Cellular Localization
- Cell membrane; Cell projection; Endoplasmic reticulum; Endosome; Postsynaptic cell membrane; Synapse
- Protein Refseq
- NP_000818.2; NP_001107655.1; NP_001244948.1
- Function
- Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "GRIA1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1504 | Rabbit Anti-GRIA1 Recombinant Antibody (clone DS1504AB) | IHC-P, IP, WB | Rabbit IgG |
| MOR-0035-FY | Rabbit Anti-GRIA1 Recombinant Antibody (clone AFY0006) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2328-CN | Rabbit Anti-GRIA1 Recombinant Antibody (clone CBACN-619) | WB, FC | Rabbit IgG |
| VS-0522-LC189 | Rat Anti-Gria1 Recombinant Antibody (VS-0522-LC189) | WB, IHC | Rat IgG2b |
| VS-0522-LC190 | Rabbit Anti-Gria1 Recombinant Antibody (VS-0522-LC190) | WB, IHC | Rabbit IgG |
| VS3-CJ949 | Rabbit Anti-GRIA1 Recombinant Antibody (VS3-CJ949) | WB, IHC, IP | Rabbit IgG |
| VS3-CJ950 | Rabbit Anti-GRIA1 (phospho S845) Recombinant Antibody (VS3-CJ950) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY115 | AbPlus™ Anti-GRIA1 Magnetic Beads (CBACN-245) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2913 | Anti-GRIA1 Immunohistochemistry Kit | IHC |
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