Rabbit Anti-GRIN2A Recombinant Antibody (VS13-YC471)
CAT#: VS13-YC471
The Rabbit Anti-GRIN2A Recombinant Antibody is specific for human, mouse and rat GRIN2A. GRIN2A, part of NMDA receptor family, influences calcium ion permeability and signaling cascades, associated with epilepsy and communication disorders through receptor activation pathways. The anti-GRIN2A antibody can be used for Western blot (1/500), Immunohistochemistry-paraffin (1/50-1/100), Immunofluorescence (1/200).
Gene Expression
Normal Tissue
Figure 1 High expression in cerebral cortex.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22725/151907_B_9_5_selected.jpg
Normal Tissue
Figure 2 Low expression in kidney.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22725/151907_A_8_5_val_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22725/151907_B_9_5.jpg
Normal Tissue
Figure 4 Cerebellum
Bergmann glia - cytoplasm/membrane Staining: Not detected Intensity: Negative Bergmann glia - nucleus Staining: Not detected Intensity: Negative GLUC cells - cytoplasm/membrane Staining: Not detected Intensity: Negative GLUC cells - nucleus Staining: Not detected Intensity: Negative Granular cells - cytoplasm/membrane Staining: Not detected Intensity: Negative Granular cells - nucleus Staining: Not detected Intensity: Negative Molecular layer - neuropil Staining: Not detected Intensity: Negative Molecular layer cells - cytoplasm/membrane Staining: Not detected Intensity: Negative Molecular layer cells - nucleus Staining: Not detected Intensity: Negative Processes in granular layer Staining: Not detected Intensity: Negative Processes in molecular layer Staining: Not detected Intensity: Negative Processes in white matter Staining: Not detected Intensity: Negative Purkinje cells - cytoplasm/membrane Staining: Not detected Intensity: Negative Purkinje cells - dendrites Staining: Not detected Intensity: Negative Purkinje cells - nucleus Staining: Not detected Intensity: Negative Synaptic glomeruli - capsule Staining: Not detected Intensity: Negative Synaptic glomeruli - core Staining: High Intensity: Strong White matter cells - cytoplasm/membrane Staining: Not detected Intensity: Negative White matter cells - nucleus Staining: Not detected Intensity: Negative
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22725/151907_B_7_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (BJ hTERT+ SV40 Large T+ RasG12V, fHDF/TERT166, hTERT-RPE1, RPMI-8226, U-138 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000183454-GRIN2A
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Specifications
- Immunogen
- Recombinant human NMDAR2A, aa 1356-1405.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat GRIN2A
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, ICC, IF
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500
Immunohistochemistry-paraffin (IHC-P): 1/50-1/100
Immunofluorescence (IF): 1/200
Target
- Alternative Names
- Glutamate Ionotropic Receptor NMDA Type Subunit 2A; Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2A; N-Methyl D-Aspartate Receptor Subtype 2A; NMDAR2A; GluN2A; NR2A; N-Methyl-D-Aspartate Receptor Channel, Subunit Epsilon-1; Glutamate [NMDA] Receptor Subunit Epsilon-1;
- Gene ID
- 2903
- UniProt ID
- Q12879
- Long Name
- Glutamate Ionotropic Receptor NMDA Type Subunit 2A
- Cellular Localization
- Cell membrane; Postsynaptic cell membrane; Dendritic spine; Synapse; Cytoplasmic vesicle membrane
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "GRIN2A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3514z | Mouse Anti-GRIN2A Recombinant Antibody (clone 41H1) | WB, ICC, IF, IHC | Mouse IgG2a |
| MRO-1099-CN | Rabbit Anti-GRIN2A Recombinant Antibody (clone JA31-20) | WB, IHC | Rabbit IgG |
| VS3-FY617 | Recombinant Rabbit Anti-Grin2A Antibody (clone R03-2K3) | WB | Rabbit IgG |
| VS7-HM1032 | Mouse Anti-GRIN2A Recombinant Antibody (clone 3G10F9) | FCM | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1511 | Rabbit Anti-GRIN2A Recombinant Antibody (clone DS1511AB) | WB | Rabbit IgG |
| MOR-0036-FY | Rabbit Anti-GRIN2A Recombinant Antibody (clone AFY0007) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0624-FY9 | Llama Anti-GRIN2A Recombinant Antibody (clone Nb-4) | IA | Lama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2921 | Anti-GRIN2A Immunohistochemistry Kit | IHC | |
| VS-0525-XY2922 | Anti-Mouse GRIN2A Immunohistochemistry Kit | IHC |
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